Concern is building about high rates of schizophrenia in large cities, and among immigrants,
cannabis users, and traumatized individuals, some of which likely reflects the causal …

Attention-deficit/hyperactivity disorder, ADHD, is a common and highly heritable
neuropsychiatric disorder that is seen in children and adults. Although heritability is …

The past decade has witnessed hundreds of reports declaring or refuting genetic
association with putative Alzheimer disease susceptibility genes. This wealth of information …

The recycling of the amyloid precursor protein (APP) from the cell surface via the endocytic
pathways plays a key role in the generation of amyloid β peptide (Aβ) in Alzheimer disease …

In an effort to pinpoint potential genetic risk factors for schizophrenia, research groups
worldwide have published over 1,000 genetic association studies with largely inconsistent …

Obsessive-compulsive disorder (OCD) is a psychiatric condition characterized by intrusive
thoughts and urges and repetitive, intentional behaviors that cause significant distress and …

There is considerable variability in the susceptibility of smokers to develop chronic
obstructive pulmonary disease (COPD). The only known genetic risk factor is severe …

Alzheimer's disease (AD) is a genetically complex and heterogeneous disorder. To date four
genes have been established to either cause early-onset autosomal-dominant AD (APP …

Obesity is a heritable trait and a risk factor for many common diseases such as type 2
diabetes, heart disease, and hypertension. We used a dense whole-genome scan of DNA …

Attention deficit hyperactivity disorder (ADHD) is a complex condition with environmental
and genetic etiologies. Up to this point, research has identified genetic associations with …