We study extreme-value statistics for spatially extended models exhibiting mixed-order
phase transitions (MOT). These are phase transitions that exhibit features common to both …

We investigate the melting transition of non-supercoiled circular DNA of different lengths,
employing Brownian dynamics simulations. In the absence of supercoiling, we find that …

One dimensional pinning models have been widely studied in the physical and
mathematical literature, also in presence of disorder. Roughly speaking, they undergo a …

We investigate the melting transition of non-supercoiled circular DNA of different lengths,
employing Brownian dynamics simulation. In the absence of supercoiling, we find that …

We investigate the denaturation dynamics of nucleic acids through extensive molecular
dynamics simulations of a coarse-grained RNA hairpin model. In apparent contradiction with …

Local opening of the DNA double helix is required in many fundamental biological
processes and is, in part, controlled by the degree of superhelicity imposed in vivo by the …

The Poland-Scheraga (PS) model is the standard basic model to study the denaturation
transition of two complementary and equally long strands of DNA. This model has enjoyed a …

Background Polymerase chain reaction (PCR) is widely used in biological research and
diagnostics because of its high sensitivity and specificity. However, the sensitivity of PCR is …