More is different in real-world multilayer networks
M De Domenico - Nature Physics, 2023 - nature.com
The constituents of many complex systems are characterized by non-trivial connectivity
patterns and dynamical processes that are well captured by network models. However, most …
patterns and dynamical processes that are well captured by network models. However, most …
[HTML][HTML] Computational approaches for network-based integrative multi-omics analysis
Advances in omics technologies allow for holistic studies into biological systems. These
studies rely on integrative data analysis techniques to obtain a comprehensive view of the …
studies rely on integrative data analysis techniques to obtain a comprehensive view of the …
Multiomics integration-based molecular characterizations of COVID-19
Abstract The coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), rapidly became a global health …
respiratory syndrome coronavirus 2 (SARS-CoV-2), rapidly became a global health …
Serverless computing in omics data analysis and integration
A comprehensive analysis of omics data can require vast computational resources and
access to varied data sources that must be integrated into complex, multi-step analysis …
access to varied data sources that must be integrated into complex, multi-step analysis …
Network analytics for drug repurposing in COVID-19
N Siminea, V Popescu… - Briefings in …, 2022 - academic.oup.com
To better understand the potential of drug repurposing in COVID-19, we analyzed control
strategies over essential host factors for SARS-CoV-2 infection. We constructed …
strategies over essential host factors for SARS-CoV-2 infection. We constructed …
[HTML][HTML] Immunomodulatory effects of new phytotherapy on human macrophages and TLR4-and TLR7/8-mediated viral-like inflammation in mice
O Schapovalova, A Gorlova, J de Munter… - Frontiers in …, 2022 - frontiersin.org
Background: While all efforts have been undertaken to propagate the vaccination and
develop remedies against SARS-CoV-2, no satisfactory management of this infection is …
develop remedies against SARS-CoV-2, no satisfactory management of this infection is …
Investigation of the Potential Mechanism of Alpinia officinarum Hance in Improving Type 2 Diabetes Mellitus Based on Network Pharmacology and Molecular Docking
X Zhang, X Li, H Li, M Zhou, Y Zhang… - Evidence‐Based …, 2023 - Wiley Online Library
Objective. We used network pharmacology, molecular docking, and cellular analysis to
explore the pharmacodynamic components and action mechanism of Alpinia officinarum …
explore the pharmacodynamic components and action mechanism of Alpinia officinarum …
[HTML][HTML] The need for a multi-level drug targeting strategy to curb the COVID-19 pandemic
GJ Kontoghiorghes, S Fetta… - Frontiers in Bioscience …, 2021 - imrpress.com
Thousands of drugs, nutraceuticals and their combinations can be used to select candidate
therapeutics for targeting SARS-CoV-2 and its symptoms in order to curb COVID-19. A …
therapeutics for targeting SARS-CoV-2 and its symptoms in order to curb COVID-19. A …
Inflammatory activation and immune cell infiltration are main biological characteristics of SARS-CoV-2 infected myocardium
R Zhang, X Chen, W Zuo, Z Ji, Y Qu, Y Su, M Yang… - …, 2022 - Taylor & Francis
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) can target
cardiomyocytes (CMs) to directly invade the heart resulting in high mortality. This study aims …
cardiomyocytes (CMs) to directly invade the heart resulting in high mortality. This study aims …
VISN: virus instance segmentation network for TEM images using deep attention transformer
C Xiao, J Wang, S Yang, M Heng, J Su… - Briefings in …, 2023 - academic.oup.com
The identification of viruses from negative staining transmission electron microscopy (TEM)
images has mainly depended on experienced experts. Recent advances in artificial …
images has mainly depended on experienced experts. Recent advances in artificial …