CD8+ T cell exhaustion and its regulatory mechanisms in the tumor microenvironment: key to the success of immunotherapy
B Zhang, J Liu, Y Mo, K Zhang, B Huang… - Frontiers in …, 2024 - frontiersin.org
A steady dysfunctional state caused by chronic antigen stimulation in the tumor
microenvironment (TME) is known as CD8+ T cell exhaustion. Exhausted-like CD8+ T cells …
microenvironment (TME) is known as CD8+ T cell exhaustion. Exhausted-like CD8+ T cells …
The role of transforming growth factor-β (TGF-β) in the formation of exhausted CD8 + T cells
R Ma, JH Sun, YY Wang - Clinical and Experimental Medicine, 2024 - Springer
CD8+ T cells exert a critical role in eliminating cancers and chronic infections, and can
provide long-term protective immunity. However, under the exposure of persistent antigen …
provide long-term protective immunity. However, under the exposure of persistent antigen …
[HTML][HTML] miR-539-5p targets BMP2 to regulate Treg activation in B-cell acute lymphoblastic leukemia through TGF-β/Smads/MAPK
Q Dai, R Shi, G Zhang, Y Wang, L Ye… - … Biology and Medicine, 2024 - ncbi.nlm.nih.gov
MicroRNAs (mRNAs) were believed to play an important role in cancers, and this study
aimed to explore the mechanism of miRNA regulating Treg in B-cell acute lymphoblastic …
aimed to explore the mechanism of miRNA regulating Treg in B-cell acute lymphoblastic …
Evaluation of NFKB1 and MyD88 expression levels in a sample of non-Hodgkin lymphoma patients before and during chemotherapy
E Rashwan, N Ibrahim, ML Salem - Egyptian Journal of Basic and …, 2024 - Taylor & Francis
Triggering of Toll-like receptors (TLRs), expressed mainly on innate immune cells, by their
specific ligands (TLRLs) induces NF-κB and MyD88, resulting in stimulation of immune …
specific ligands (TLRLs) induces NF-κB and MyD88, resulting in stimulation of immune …
T cell exhaustion: Supremacy in leukemia as for disease and therapy
NK Mohamed, MA El-Mokhtar… - Bulletin of …, 2024 - bpsa.journals.ekb.eg
In this review, an overview of exhausted T cells in acute and chronic leukemias including
myelocytic and lymphoblastic leukemia was made to browse this important subset of cells …
myelocytic and lymphoblastic leukemia was made to browse this important subset of cells …