Quality by design approach for fabrication of extended-release buccal films for xerostomia employing hot-melt extrusion technology

RM Elkanayati, AY Darwesh, I Taha, H Wang… - European Journal of …, 2024 - Elsevier
The study endeavors the fabrication of extended-release adipic acid (APA) buccal films
employing a quality by design (QbD) approach. The films intended for the treatment of …

Investigating a novel therapeutic composition for dry eye syndrome management: In vitro and in vivo studies

D Rana, J Beladiya, D Sheth, H Kumar… - International Journal of …, 2024 - Elsevier
Dry eye syndrome (DES) presents a significant challenge in ophthalmic care, necessitating
innovative approaches for effective management. This research article introduces a …

Formulation Development and Evaluation of Cannabidiol Hot-Melt Extruded Solid Self-Emulsifying Drug Delivery System for Oral Applications

K Sanil, A Almotairy, P Uttreja, EA Ashour - AAPS PharmSciTech, 2024 - Springer
Cannabidiol (CBD) is a highly lipophilic compound with poor oral bioavailability, due to poor
aqueous solubility and extensive pre-systemic metabolism. The aim of this study was to …

Design of quetiapine fumarate loaded polyethylene glycol decorated graphene oxide nanosheets: In vitro-ex vivo characterization

GS Patil, SN Nangare, DA Patil, DD Borhade… - Annales …, 2024 - Elsevier
Quetiapine Fumarate (QF) is an atypical antipsychotic with poor oral bioavailability (9%) due
to its low permeability and pH-dependent solubility. Therefore, this study aims to design QF …

Formulation development of simvastatin self-emulsifying drug delivery system using Hot melt extrusion

S Chilamula - 2024 - search.proquest.com
Simvastatin, a potent HMG-CoA reductase inhibitor, lowers cholesterol levels. It prevents
cardiovascular events like heart attacks and strokes in patients with high cholesterol and …

[PDF][PDF] Research News, Publications, 2021, Volume 3

S Majumdar - 2021 - egrove.olemiss.edu
22. De La Cruz LK, Yang X, Menshikh A, Brewer M, Lu W, Wang M, Wang S, Ji X, Cachuela
A, Yang H, Gallo D, Tan C, Otterbein L, de Caestecker M, Wang B. Adapting decarbonylation …