Immunological mechanisms have come into the focus of current translational stroke
research, and the modulation of neuroinflammatory pathways has been identified as a …

Besides damaging the brain, stroke causes systemic changes, including to the
gastrointestinal system. A growing body of evidence supports the role of the gut and its …

Objective Stroke is a leading cause of death and disability worldwide. Neuroprotective
approaches have failed in clinical trials, thus warranting therapeutic innovations with …

Recent research on the gut microbiome has revealed the influence of gut microbiota (GM)
on ischemic stroke pathogenesis and treatment outcomes. Alterations in the diversity …

The intestinal microbiome, the largest reservoir of microorganisms in the human body, plays
an important role in neurological development and aging as well as in brain disorders such …

Ischaemic stroke is a leading cause of disability and death for which no acute treatments
exist beyond recanalization. The development of novel therapies has been repeatedly …

Acute central nervous system (CNS) injuries, including stroke, traumatic brain injury (TBI),
and spinal cord injury (SCI), are the common causes of death or lifelong disabilities …

Unrestrained excessive inflammatory responses exacerbate ischemic brain injury and
impede post-stroke brain recovery. CD4+ CD25+ Foxp3+ regulatory T (Treg) cells play …

Stroke is a leading cause of morbidity and mortality worldwide. It inflicts immeasurable
suffering on patients and their loved ones and carries an immense social cost. Efforts to …

Gut microbiota has implications in Central Nervous System (CNS) disorders. Our study
systematically identified preclinical studies aimed to investigate the possible gut microbiota …