TMBstable: a variant caller controls performance variation across heterogeneous sequencing samples
S Wang, X Zhu, X Wang, Y Liu, M Zhao… - Briefings in …, 2024 - academic.oup.com
In cancer genomics, variant calling has advanced, but traditional mean accuracy evaluations
are inadequate for biomarkers like tumor mutation burden, which vary significantly across …
are inadequate for biomarkers like tumor mutation burden, which vary significantly across …
A Statistical Explainable Learning Model Optimizing Co-localization of Multidimensional Positivity Thresholds in Immunotherapy Decision-Supporting
Y Wang, J Liu, J Zhao, J Wang… - … on Bioinformatics and …, 2023 - ieeexplore.ieee.org
Tumor Mutation Burden (TMB) serves as a recognized stratified biomarker for
immunotherapy. However, its one-dimensional representation of non-synonymous genetic …
immunotherapy. However, its one-dimensional representation of non-synonymous genetic …