Lipid rafts are critical cell membrane lipid platforms enriched in sphingolipid and cholesterol
content involved in diverse cellular processes. They have been proposed to influence …

Glioblastoma (GBM) is the most aggressive brain tumor in adults and is characterized by an
immunosuppressive microenvironment. Different factors shaping this tumor …

Background Uveal melanoma (UVM) is the most common primary intraocular malignancy in
adults and is highly metastatic, resulting in a poor patient prognosis. Sphingolipid …

Drug resistance continues to be one of the major challenges to cure cancer. As research in
this field evolves, it has been proposed that numerous bioactive molecules might be …

Metabolic Reprogramming is a sign of tumor, and as one of the three major substances
metabolism, lipid has an obvious impact. Abnormal lipid metabolism is related to the …

Simple Summary Metabolic reprogramming in glioblastoma is a hallmark of malignancy.
Metabolic enzymes and metabolites participate in energetic metabolism and function as …

Metastasis is considered to be responsible for 90% of cancer-related deaths. Although it is
clinically evident that metastatic patterns vary by primary tumor type, the molecular …

Phospholipases are enzymes that cleave ester bonds within phospholipids. As a
consequence of these hydrolysis reactions, a variety of lipid products are generated, which …

Background Growing evidence suggests the gut microbiota and metabolites in serum or
fecal may play a key role in the process of alcohol use disorder (AUD). However, the …

Glioblastoma multiforme (GBM) is the most common and aggressive primary brain tumour in
adults. Treatments include surgical resection, radiotherapy, and chemotherapy. Despite this …