[HTML][HTML] Optimizing antibiotic therapies to reduce the risk of bacterial resistance

S Bassetti, S Tschudin-Sutter, A Egli… - European journal of …, 2022 - Elsevier
The incidence of infections caused by bacteria that are resistant to antibiotics is constantly
increasing. In Europe alone, it has been estimated that each year about 33′ 000 deaths are …

Advancing global antibiotic research, development and access

LJV Piddock, Y Alimi, J Anderson, D de Felice… - Nature Medicine, 2024 - nature.com
The pipeline of new antibiotics is insufficient to keep pace with the growing global burden of
drug-resistant infections. Substantial economic challenges discourage private investment in …

Worldwide traceability of antibiotic residues from livestock in wastewater and soil: A systematic review

LE Robles-Jimenez, E Aranda-Aguirre… - Animals, 2021 - mdpi.com
Simple Summary This work focuses on reviewing research works on antibiotic residues,
evaluating antibiotics used in livestock production and their excretion in animal products and …

[HTML][HTML] Nanoantibiotics to fight multidrug resistant infections by Gram-positive bacteria: hope or reality?

F Berini, V Orlandi, R Gornati, G Bernardini… - Biotechnology …, 2022 - Elsevier
The spread of antimicrobial resistance in Gram-positive pathogens represents a threat to
human health. To counteract the current lack of novel antibiotics, alternative antibacterial …

Antibiotic consumption in India: geographical variations and temporal changes between 2011 and 2019

S Fazaludeen Koya, S Ganesh… - JAC-Antimicrobial …, 2022 - academic.oup.com
Objectives To describe and compare private sector systemic (J01) antibiotic consumption
across Indian states from 2011 to 2019. Methods We used the nationally representative …

Antibiotic use in China's public healthcare institutions during the COVID-19 pandemic: an analysis of nationwide procurement data, 2018–2020

Y Yang, X Geng, X Liu, X Wen, R Wu, D Cui… - Frontiers in …, 2022 - frontiersin.org
Background: The overuse of antibiotics is a serious public health problem and a major
challenge in China, and China lacks up-to-date evidence on the nationwide antibiotic use in …

Prevalence and distribution of antimicrobial resistance in effluent wastewater from animal slaughter facilities: A systematic review

L Foyle, M Burnett, A Creaser, R Hens, J Keough… - Environmental …, 2023 - Elsevier
The extensive use of antibiotics in food animal production and disposal of untreated
wastewater from food animal slaughter facilities may create a shift in microbiomes of …

[HTML][HTML] Chemical composition, antioxidant, antimicrobial and antiproliferative activity of Laureliopsis philippiana essential oil of Chile, study in vitro and in silico

F Bruna, K Fernández, F Urrejola, J Touma… - Arabian Journal of …, 2022 - Elsevier
Chilean Laureliopsis philippiana has been used in traditional medicine by the Mapuche and
their ancestors. To evaluate its pharmacological activity, Laureliopsis philippiana leaf …

[HTML][HTML] WHO's essential medicines and AWaRe: recommendations on first-and second-choice antibiotics for empiric treatment of clinical infections

L Moja, V Zanichelli, D Mertz, S Gandra… - Clinical Microbiology …, 2024 - Elsevier
Abstract The WHO Model List of Essential Medicines (EML) prioritizes medicines that have
significant global public health value. The EML can also deliver important messages on …

Gut metagenome associations with extensive digital health data in a volunteer-based Estonian microbiome cohort

O Aasmets, KL Krigul, K Lüll, A Metspalu… - Nature …, 2022 - nature.com
Microbiome research is starting to move beyond the exploratory phase towards
interventional trials and therefore well-characterized cohorts will be instrumental for …