Childhood cancers are life-threatening diseases that are universally distressing and
potentially traumatic for children and their families at diagnosis, during treatment, and …

Survivors of childhood cancer frequently experience cancer-related cognitive dysfunction,
commonly months to years after treatment for pediatric brain tumors, acute lymphoblastic …

PURPOSE Children with average-risk medulloblastoma (MB) experience survival rates of≥
80% at the expense of adverse consequences of treatment. Efforts to mitigate these effects …

Importance Brain tumors are the leading cause of disease-related death in children.
Medulloblastoma is the most common malignant embryonal brain tumor, and strategies to …

PURPOSE Stratum 1 of ACNS1123 (ClinicalTrials. gov identifier: NCT01602666), a
Children's Oncology Group phase II trial, evaluated efficacy of reduced-dose and volume of …

Central nervous system cancers or exposure to CNS‐directed therapies increase risk for
neuropsychological deficits. There are no accepted guidelines for assessment of …

Medulloblastoma is the most common malignant brain tumor of childhood. While prognosis
has significantly improved in the last decades with multimodal therapy including surgery …

Cancer-related cognitive impairment is a broad term encompassing subtle cognitive
problems to more severe impairment. The severity of this impairment is influenced by host …

Medulloblastoma is the most common embryonal tumor of the central nervous system in
childhood. Combined multimodality approaches, including surgery, radiation, and …

Introduction There is increasing recognition of the long-term sequelae of brain tumours
treated in childhood. Five year survival rates now exceed 75% and assessing the quality of …