Vitamin A is the first vitamin approved by the Food and Drug Administration as an anti-
wrinkle agent that changes appearance of the skin surface and has anti-aging effects …

Vitamin A or retinol is arguably the most multifunctional vitamin in the human body, as it is
essential from embryogenesis to adulthood. The pleiotropic effects of vitamin A are exerted …

Abstract Cellular binding-proteins (BP), including CRBP1, CRBP2, CRABP1, CRABP2, and
FABP5, shepherd the poorly aqueous soluble retinoids during uptake, metabolism and …

Retinoids (vitamin A) are crucial for most forms of life. In chordates, they have important roles
in the developing nervous system and notochord and many other embryonic structures, as …

Transcriptional activation of the nuclear receptor RAR by retinoic acid (RA) often leads to
inhibition of cell growth. However, in some tissues, RA promotes cell survival and …

In the immune system, the vitamin A metabolite retinoic acid (RA) is known for its role in
inducing gut-homing molecules in T and B cells, inducing regulatory T cells (Tregs), and …

Vitamin A is a multifunctional vitamin implicated in a wide range of biological processes. Its
control over the immune system and functions are perhaps the most pleiotropic not only for …

The intracellular fatty acid-binding proteins (FABPs) comprise a family of 14–15 kDa proteins
which bind long-chain fatty acids. A role for FABPs in fatty acid transport has been …

Lipophilic compounds such as retinoic acid and long-chain fatty acids regulate gene
transcription by activating nuclear receptors such as retinoic acid receptors (RARs) and …

Vitamin A is essential for the formation and maintenance of many body tissues. It is also
important for embryonic growth and development and can act as a teratogen at critical …