Galectins are a family of endogenous glycan-binding proteins that have crucial roles in a
broad range of physiological and pathological processes. As a group, these proteins use …

Galectins are carbohydrate-binding proteins that are involved in many physiological
functions, such as inflammation, immune responses, cell migration, autophagy and …

Chimeric antigen receptor (CAR) T cells targeting CD19 have achieved breakthroughs in the
treatment of hematological malignancies, such as relapsed/refractory non-Hodgkin …

Herein we will review the role of glycans in the immune system. Specific topics covered
include: the glycosylation sites of IgE, IgM, IgD, IgE, IgA, and IgG; how glycans can encode …

Abstract Galectin-3 is a 31-kDa lectin that modulates T-cell responses through several
mechanisms, including apoptosis, T-cell receptor (TCR) cross-linking, and TCR …

Galectins are glycan-binding proteins that contain one or two carbohydrate domains and
mediate multiple biological functions. By analyzing clinical tumor samples, the abnormal …

Galectins are a family of widely expressed β-galactoside-binding lectins in metazoans. The
15 mammalian galectins have either one or two conserved carbohydrate recognition …

Most cell surface proteins are decorated by glycans, and the plasma membrane is rich in
glycosylated lipids. The mechanisms by which the enormous complexity of these glycan …

Galectin 3 is a member of a family of β-galactoside binding proteins and has emerged as an
important regulator of diverse functions critical in cancer biology including apoptosis …

Galectins are a family of mammalian carbohydrate-binding proteins expressed by many cell
types. Galectins can function intracellularly and can also be secreted to bind to cell surface …