Amniotic membrane (AM) or amnion is a thin membrane on the inner side of the fetal
placenta; it completely surrounds the embryo and delimits the amniotic cavity, which is filled …

An important component of tissue engineering (TE) is the supporting matrix upon which cells
and tissues grow, also known as the scaffold. Scaffolds must easily integrate with host tissue …

Materials and Methods This is a prospective, interventional, consecutive case series
conducted at Careggi Hospital affiliated with Florence University School of Medicine. All the …

One of the main goals of tissue engineering and regenerative medicine is to develop skin
substitutes for treating deep dermal and full thickness wounds. In this regard, both scaffold …

In the past 20 years, human amniotic membrane (AM) has become widely used as an
ophthalmic surgical patch as well as a substrate for stem cell tissue equivalents for ocular …

The retinal pigment epithelium (RPE) maintains retinal function as the metabolic gatekeeper
between photoreceptors (PRs) and the choriocapillaries. The RPE and Bruch's membrane …

Background Several mechanisms of retina degeneration result in the deterioration of the
outer retina and can lead to blindness. Currently, with the exception of anti-angiogenic …

Retinal pigment epithelial (RPE) cells have several functions, including support of the neural
retina and choroid in the eye and immunosuppression. Cultured human RPE cells directly …

Age‐related macular degeneration (AMD) is the leading cause of blindness in the Western
world. With an ageing population, it is anticipated that the number of AMD cases will …

Human pluripotent stem cell-derived retinal pigment epithelium (iRPE) is an attractive cell
source for disease modeling and cell replacement therapy of retinal disorders with RPE …