Pathogenicity and virulence of the liver flukes Fasciola hepatica and Fasciola Gigantica that cause the zoonosis Fasciolosis

R Lalor, K Cwiklinski, NED Calvani, A Dorey, S Hamon… - Virulence, 2021 - Taylor & Francis
Fasciolosis caused by the liver flukes Fasciola hepatica and Fasciola gigantica is one of the
most important neglected parasitic diseases of humans and animals. The ability of the …

An Update on the Pathogenesis of Fascioliasis: What Do We Know?

MB Tanabe, MA Caravedo… - … and Reports in …, 2024 - Taylor & Francis
Fasciola hepatica is a trematode parasite distributed worldwide. It is known to cause disease
in mammals, producing significant economic loses to livestock industry and burden to …

Autonomous Non Antioxidant Roles for Fasciola hepatica Secreted Thioredoxin-1 and Peroxiredoxin-1

A Dorey, K Cwiklinski, J Rooney… - Frontiers in cellular …, 2021 - frontiersin.org
Trematode parasites of the genus Fasciola are the cause of liver fluke disease (fasciolosis)
in humans and their livestock. Infection of the host involves invasion through the intestinal …

Macrophage Gal/GalNAc lectin 2 (MGL2)+ peritoneal antigen presenting cells during Fasciola hepatica infection are essential for regulatory T cell induction

M Costa, V da Costa, P Lores, M Landeira… - Scientific Reports, 2022 - nature.com
Fasciola hepatica, one of the agents that causes fasciolosis, modulates the host immune
system to allow parasite survival in the host. F. hepatica expresses carbohydrate-containing …

Heme-Oxygenase-1 Attenuates Oxidative Functions of Antigen Presenting Cells and Promotes Regulatory T Cell Differentiation during Fasciola hepatica Infection

M Costa, V da Costa, S Frigerio, MF Festari… - Antioxidants, 2021 - mdpi.com
Fasciola hepatica is a fluke that infects livestock and humans causing fasciolosis, a zoonotic
disease of increasing importance due to its worldwide distribution and high economic …

Construction of a multiepitope vaccine candidate against Fasciola hepatica: an in silico design using various immunogenic excretory/secretory antigens

M Akıl, M Aykur, M Karakavuk, H Can… - Expert review of …, 2022 - Taylor & Francis
Background Fasciola hepatica is an important pathogen that causes liver fluke disease in
definitive hosts such as livestock animals and humans. Various excretory/secretory products …

In vitro and in vivo studies on a group of chalcones find promising results as potential drugs against fascioliasis

Z Artía, F Ferraro, C Sánchez, H Cerecetto, J Gil… - Experimental …, 2023 - Elsevier
About a third of the world population is infected by helminth parasites implicated in
foodborne trematodiasis. Fascioliasis is a worldwide disease caused by trematodes of the …

Liver function markers and haematological dynamics during acute and chronic phases of experimental Fasciola hepatica infection in cattle treated with triclabendazole

M Costa, A Saravia, D Ubios, P Lores, V da Costa… - Experimental …, 2022 - Elsevier
Fasciola hepatica, a worldwide-distributed liver fluke, is one of the causative agents of
fasciolosis, a zoonotic disease that affects livestock and humans. In livestock, fasciolosis …

Exploration of animal models to study the life cycle of Fasciola hepatica

W Fang, J Yang, H Wang, S Chen, K Li, Y Liu, Y Duan… - Parasitology, 2022 - cambridge.org
The parasite Fasciola hepatica is an important zoonotic parasite. The development of an
animal model of F. hepatica's life cycle is critical for studying the biological characteristics of …

Bovine Natural Antibody Relationships to Specific Antibodies and Fasciola hepatica Burdens after Experimental Infection and Vaccination with Glutathione S …

G Zerna, TC Cameron, H Toet, TW Spithill… - Veterinary Sciences, 2022 - mdpi.com
Fasciola hepatica is the causative agent of fasciolosis, a significant parasitic disease
occurring worldwide. Despite ongoing efforts, there is still no vaccine to control liver fluke …