Bacterial infections represent a significant health threat globally, and are responsible for the
majority of hospital-acquired infections, leading to extensive mortality and burden on global …

The biological activity of Mannich bases, a structurally heterogeneous class of chemical
compounds that are generated from various substrates through the introduction of an …

Fluoroquinolones remain one of the most important kind of antibacterial agents used
nowadays. The emergence of more virulent and resistant strains of bacteria by the …

The emergence and wide-spread of drug-resistant bacteria including multi-drug resistant
and pan-drug resistant pathogens which are associated with considerable mortality …

Gram-positive bacteria are responsible for a broad range of infectious diseases, and the
emergency and wide spread of drug-resistant Gram-positive pathogens including MRSA …

Piperazine is one of the most sought heterocyclics for the development of new drug
candidates. This ring can be traced in a number of well established, commercially available …

Escherichia coli (E. coli) is the most common pathogen in both hospital and community
settings, and is capable of causing infections that can lead to serious consequences …

Chitosan and kojic acid composite films (CHn-KAm) utilizing three chitosan with differing
molecular weights and kojic acid in different ratios were investigated. Results showed that …

A series of kojic acid-derived compounds 6a-p bearing aryloxymethyl-1H-1, 2, 3-triazol-1-yl
moiety were designed by modifying primary alcoholic group of kojic acid as tyrosinase …

Here, a nontoxic antibacterial material based on Chitosan Oligosaccharide-N-Chlorokojic
acid Mannich base (COS-N-MB) that was synthesized by using the selective partial …