Flavin-dependent monooxygenases (FDMOs) are known for their remarkable versatility and
for their crucial roles in various biological processes and applications. Extensive research …

Strategies for achieving asymmetric catalysis with azaarenes have traditionally fallen short
of accomplishing remote stereocontrol, which would greatly enhance accessibility to distinct …

In recent decades, the traceless nature of visible photons has been exploited for the
development of efficient synthetic strategies for the photoconversion of colourless …

Controlling the enantioselectivity of hydrogen atom transfer (HAT) reactions has been a long-
standing synthetic challenge. While recent advances on photoenzymatic catalysis have …

The enantioselective reduction of enamides is an efficient and atom-economical way to
construct chiral amine motifs. In contrast to transition-metal complex based asymmetric …

Aromatic electron-deficient heterocycles, such as pyridines, are found in many biologically
relevant structures, including those with medicinal applications. Methods for their …

Enzymes capable of assimilating fluorinated feedstocks are scarce. This situation poses a
challenge for the biosynthesis of fluorinated compounds used in pharmaceuticals …

Artificial photoenzymes with novel catalytic modes not found in nature are in high demand;
yet, they also present significant challenges in the field of biocatalysis. In this study, a …

Visible light-driven pyridoxal radical biocatalysis has emerged as a promising strategy for
the stereoselective synthesis of valuable noncanonical amino acids (ncAAs). Previously, the …

Photoenzymatic intermolecular hydroalkylations of olefins are highly enantioselective for
chiral centers formed during radical termination but poorly selective for centers set in the C …