Urinary tract infections (UTIs) are among the most frequent infectious diseases affecting
humans, and represent an important public health problem with a substantial economic …

β-lactamases are the primary cause of resistance to β-lactams among members of the family
Enterobacteriaceae. SHV enzymes have emerged in Enterobacteriaceae causing infections …

Klebsiella pneumoniae is an important opportunistic pathogen that commonly causes
nosocomial infections and contributes to substantial morbidity and mortality. We sought to …

Inactivation of β‐lactam antibiotics by β‐lactamases in bacterial infections is associated with
some of the most serious infectious disease issues that are currently encountered. The …

The model of biofilm infection was first proposed over a decade ago. Recent scientific
advances have added much to our understanding of biofilms, usually polymicrobial …

Surveillance of antimicrobial agent resistance provides important information to guide
microbiologists and infectious disease specialists understanding of the control and the …

Extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae present an ever-
growing burden in the hospital and community settings, across all ages and demographics …

The in vitro activity of ceftazidime-avibactam was evaluated against 34,062 isolates of
Enterobacteriaceae from patients with intra-abdominal, urinary tract, skin and soft-tissue …

The spread of β-lactamases that hydrolyze penicillins, cephalosporins and carbapenems
among Gram-negative bacteria has limited options for treating bacterial infections. Initially …

Microbial populations which are resistant to antibiotics are an emerging environmental
concern with potentially serious implications for public health. Thus, there is a growing …