Influenza viral vector based Brucella abortus vaccine: a novel vaccine candidate for veterinary practice

K Tabynov - Expert Review of Vaccines, 2016 - Taylor & Francis
Bovine brucellosis is caused by the gram-negative Brucella abortus bacterium and induces
abortion and decreased fertility that lead to significant economic losses in agriculture, and is …

[PDF][PDF] Molecular typing methods to characterize Brucella spp. from animals: A review.

A Daugaliyeva, S Daugaliyeva, N Kydyr… - Veterinary …, 2024 - veterinaryworld.org
Brucellosis is an infectious disease of animals that can infect humans. The disease causes
significant economic losses and threatens human health. A timely and accurate disease …

Improved influenza viral vector based Brucella abortus vaccine induces robust B and T-cell responses and protection against Brucella melitensis infection in …

A Mailybayeva, B Yespembetov, S Ryskeldinova… - PLoS …, 2017 - journals.plos.org
We previously developed a potent candidate vaccine against bovine brucellosis caused by
Brucella abortus using the influenza viral vector expressing Brucella Omp16 and L7/L12 …

Vaccine safety studies of Brucella abortus S19 and S19ΔvjbR in pregnant swine

S Zriba, DG Garcia-Gonzalez, OH Khalaf, L Wheeler… - Vaccine: X, 2019 - Elsevier
Brucellosis in swine is caused by Brucella suis, a bacterial infection of nearly worldwide
distribution. Brucella suis is also transmissible to humans, dogs and cattle and is considered …

First evaluation of an influenza viral vector based Brucella abortus vaccine in sheep and goats: Assessment of safety, immunogenicity and protective efficacy against …

K Tabynov, B Yespembetov, N Matikhan… - Veterinary …, 2016 - Elsevier
Previously we developed and evaluated a candidate influenza viral vector based Brucella
abortus vaccine (Flu-BA) administered with a potent adjuvant Montanide Gel01 in cattle …

An influenza viral vector Brucella abortus vaccine induces good cross-protection against Brucella melitensis infection in pregnant heifers

K Tabynov, S Ryskeldinova, A Sansyzbay - Vaccine, 2015 - Elsevier
Brucella melitensis can be transmitted and cause disease in cattle herds as a result of
inadequate management of mixed livestock farms. Ideally, vaccines against Brucella abortus …

Prime-booster vaccination of cattle with an influenza viral vector Brucella abortus vaccine induces a long-term protective immune response against Brucella abortus …

K Tabynov, B Yespembetov, S Ryskeldinova, N Zinina… - Vaccine, 2016 - Elsevier
This study analyzed the duration of the antigen-specific humoral and T-cell immune
responses and protectiveness of a recently-developed influenza viral vector Brucella …

Registered Influenza Viral Vector Based Brucella abortus Vaccine for Cattle in Kazakhstan: Age-Wise Safety and Efficacy Studies

S Ryskeldinova, N Zinina, Z Kydyrbayev… - Frontiers in cellular …, 2021 - frontiersin.org
A novel influenza viral vector based Brucella abortus vaccine (Flu-BA) was introduced for
use in cattle in Kazakhstan in 2019. In this study, the safety and efficacy of the vaccine was …

Whole Genome Sequence Analysis of Brucella abortus Isolates from Various Regions of South Africa

MB Ledwaba, BA Glover, I Matle, G Profiti, PL Martelli… - Microorganisms, 2021 - mdpi.com
The availability of whole genome sequences in public databases permits genome-wide
comparative studies of various bacterial species. Whole genome sequence-single …

Simultaneous subcutaneous and conjunctival administration of the influenza viral vector based Brucella abortus vaccine to pregnant heifers provides better protection …

K Tabynov, M Orynbayev, GJ Renukaradhya… - Vaccine, 2016 - Elsevier
In this study, we explored possibility of increasing the protective efficacy of our novel
influenza viral vector based B. abortus vaccine (Flu-BA) in pregnant heifers by adapting an …