Fluorine does not belong to the pool of chemical elements that nature uses to build organic
matter. However, chemists have exploited the unique properties of fluorine and produced …

Alkylations of chiral or achiral Ni (II) complexes of glycine Schiff bases constitute a landmark
in the development of practical methodology for asymmetric synthesis of α-amino acids …

This review provides a comprehensive treatment of literature data dealing with asymmetric
synthesis of α-amino-β-hydroxy and α, β-diamino acids via homologation of chiral Ni (II) …

The major goal of this review is a critical discussion of the literature data on asymmetric
synthesis of α-amino acids via Michael addition reactions involving Ni (II)-complexes of …

Abstract Development of synthetic methodology for preparation of enantiomerically pure
fluorine containing amino acids (FAAs) is one of the most actively pursued areas of …

Naturally occurring compounds containing a CF bond are extremely rare; only a handful of
fluorine-containing carboxylic acids have been described so far. By contrast, man-made …

This report provides an overview of the practical methods for preparing symmetrically α, α-
disubstituted α-amino acids and their derivatives. Despite the growing application of this …

Conclusions Thus this review gives explicit information about the versatility and importance
of pyroglutamate with special attention to asymmetric synthesis of bioactive molecules …

The synthesis of unnatural α-amino acids is an area of research that has gained a lot of
attention in recent years. The availability of synthetic methods for novel unnatural α-amino …

This paper describes a practical, enantio-and diastereoselective Mannich reaction between
a chiral Ni (II) complex of glycine 1 and α-amino sulfones 2, involving the creation of a …