Cachexia, a systemic wasting condition, is considered a late consequence of diseases,
including cancer, organ failure, or infections, and contributes to significant morbidity and …

Sarcopenic obesity, or the loss of muscle mass and function associated with excess
adiposity, is a largely untreatable medical condition associated with diminished quality of life …

The transforming growth factor-β (TGFβ) family are a large group of evolutionarily conserved
cytokines whose signalling modulates cell fate decision-making across varying cellular …

Cachexia is a major cause of morbidity and mortality in individuals with cancer and is
characterized by weight loss due to adipose and muscle tissue wasting. Hallmarks of white …

Muscle wasting is a serious comorbidity associated with many disorders, including cancer,
kidney disease, heart failure, and aging. Progressive loss of skeletal muscle mass …

Epithelial cell adhesion molecule (EpCAM) is a type I transmembrane glycoprotein, which is
highly expressed on tumor cells. As EpCAM plays a crucial role in cell adhesion, survival …

Adipokines play a significant role in cardiometabolic diseases. Asprosin, a newly discovered
adipokine, was first identified as a glucose-raising protein hormone. Asprosin also …

Abstract Background About 10% of NSCLCs are mutated in KRAS and impaired in
STK11/LKB1, a genetic background associated with poor prognosis, caused by an increase …

A festa “à brasileira”, constitui uma linguagem simbólica para a qual são traduzidos muitos
dos valores nacionais. Ela é capaz de mediar diferenças sociais e culturais, estabelecendo …

Cancer is a major cause of global mortality, both in affluent countries and increasingly in
developing nations. Many patients with cancer experience reduced life expectancy and …