The role of systemic microvascular dysfunction in heart failure with preserved ejection fraction

J Weerts, SGJ Mourmans, A Barandiaran Aizpurua… - Biomolecules, 2022 - mdpi.com
Heart failure with preserved ejection fraction (HFpEF) is a condition with increasing
incidence, leading to a health care problem of epidemic proportions for which no curative …

The effect of gender-affirming hormone therapy on the risk of subclinical atherosclerosis in the transgender population: a systematic review

RMCM Allgayer, G da Silva Borba, RS Moraes… - Endocrine Practice, 2023 - Elsevier
Objective The impact of gender-affirming hormone therapy (GAHT) on cardiovascular (CV)
health is still not entirely established. A systematic review was conducted to summarize the …

Detrimental effects of physical inactivity on peripheral and brain vasculature in humans: Insights into mechanisms, long-term health consequences and protective …

A Daniele, SJE Lucas, C Rendeiro - Frontiers in Physiology, 2022 - frontiersin.org
The growing prevalence of physical inactivity in the population highlights the urgent need for
a more comprehensive understanding of how sedentary behaviour affects health, the …

Effects of isoflavones on the skin of postmenopausal women: a pilot study

A Accorsi-Neto, M Haidar, R Simões, M Simões… - Clinics, 2009 - SciELO Brasil
OBJECTIVE: The aim of this study was to evaluate the effects of isoflavones on the skin of
postmenopausal women. DESIGN: A prospective study was performed with 30 …

High prevalence of increased interleukin-17A serum levels in postmenopausal estrogen deficiency

I Molnár, I Bohaty, É Somogyiné-Vári - Menopause, 2014 - journals.lww.com
Objective Postmenopausal estrogen deficiency is associated with chronic inflammatory
events that cause cardiovascular and osteoporosis diseases. The aim of this study was to …

Roles of oxidants, nitric oxide, and asymmetric dimethylarginine in endothelial function

R Siekmeier, T Grammer… - Journal of cardiovascular …, 2008 - journals.sagepub.com
Vascular endothelium plays a crucial role in ensuring normal function and morphology of
blood vessels, and many risk factors of atherosclerosis act via their effects on endothelial …

Estrogen-mediated protection against coronary heart disease: The role of the Notch pathway

F Fortini, FV Dalla Sega, C Caliceti, E Lambertini… - The Journal of steroid …, 2019 - Elsevier
Estrogen regulates a plethora of biological processes, under physiological and pathological
conditions, by affecting key pathways involved in the regulation of cell proliferation, fate …

Influence of aging and menopause on lipids and lipoproteins in women

GD Kolovou, HG Bilianou - Angiology, 2008 - journals.sagepub.com
The actions of endogenous estrogens on the cardiovascular system can be mediated
directly on the vessels or indirectly through the modulation of cardiovascular risk factors …

Transformation or replacement-Effects of hormone therapy on cardiovascular risk

J Kielb, S Saffak, J Weber, L Baensch… - Pharmacology & …, 2024 - Elsevier
Hormone therapy (HT) is important and frequently used both regarding replacement therapy
(HRT) and gender affirming therapy (GAHT). While HRT has been effective in addressing …

Serum vitamin C concentration and hs-CRP level in middle-aged Japanese men and women

Y Kubota, Y Moriyama, K Yamagishi, T Tanigawa… - Atherosclerosis, 2010 - Elsevier
OBJECTIVE: To examine the association between concentrations of serum vitamin C, a
contributive factor to prevention of cardiovascular disease and levels of hs-CRP, a risk factor …