Natural products (NPs) are a rich source of structurally novel molecules, and the chemical
space they encompass is far from being fully explored. Over history, NPs have represented a …

Natural products have a significant role in drug discovery. Natural products have distinctive
chemical structures that have contributed to identifying and developing drugs for different …

Natural products continue to be major sources of bioactive compounds and drug candidates
not only because of their unique chemical structures but also because of their overall …

The abnormal expression of the c-Met tyrosine kinase has been linked to the proliferation of
several human cancer cell lines, including non-small-cell lung cancer (NSCLC). In this …

Diabetes mellitus termed as metabolic disorder is a collection of interlinked diseases and
mainly body's inability to manage glucose level which leads to cardiovascular diseases …

The severe acute respiratory syndrome coronavirus-2 (SARS CoV-2) is β-coronavirus that is
responsible for the pandemic coronavirus disease 2019 (COVID-19) all over the world. The …

Introduction: In this work, we used several molecular modeling techniques to design new
molecules for the treatment of non-small cell lung cancer (NSCLC). Methods: For this …

Phytocompounds are a well-established source of drug discovery due to their unique
chemical and functional diversities. In the area of cancer therapeutics, several …

The current study reveals the inhibitory potential of novel bioactive compounds of mangrove
actinomycetes against nsp10 of SARS-CoV-2. A total of fifty (50) novel bioactive …

Despite COVID-19 vaccination, immune escape of new SARS-CoV-2 variants has created
an urgent priority to identify additional antiviral drugs. Targeting main protease (Mpro) …