Age is a primary risk factor for a number of chronic diseases including mobility disability,
cardiovascular disease (CVD), type 2 diabetes (T2D), and cancer. Most physical activity …

Background Low physical activity has been shown to be one of the most common
components of frailty, and interventions have been considered to prevent or reverse this …

Aim Exercise is one of the most important components in frailty prevention and treatment.
Therefore, we systematically reviewed the effect of resistance training (RT) alone or …

The aim of this review was to recommend training strategies that improve the functional
capacity in physically frail older adults based on scientific literature, focusing specially in …

Regular exercise has multi-system anti-aging effects. Here we summarize how exercise
impacts the major hallmarks of aging. We propose that, besides searching for novel …

Human aging results in a variety of changes to skeletal muscle. Sarcopenia is the age-
associated loss of muscle mass and is one of the main contributors to musculoskeletal …

Background evidence on the effectiveness of interventions to prevent frailty is scarce.
Objective to assess the effect of an intervention in preventing frailty progression in pre-frail …

Aging is associated with declines in the neuromuscular and cardiovascular systems,
resulting in an impaired capacity to perform daily activities. Frailty is an age-associated …

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Creative Commons Attribution-NonCommercial-ShareAlike 3.0 IGO (CC BY-NC-SA 3.0 IGO; …

Frailty syndrome encompasses several physical hallmarks such as loss of muscle strength,
power output and mass, which leads to poor gait ability, fatigue, falls and overall difficulty to …