Application of modern and innovative spectroscopic and microscopic approaches to
biomedical analysis opens new horizons and sheds new light on many unexplored scientific …

Antibody–drug conjugates (ADCs) constitute a relatively new group of anticancer agents,
whose first appearance took place about two decades ago, but a renewed interest occurred …

In total, 279 patients with hairy-cell leukemia (HCL) were analyzed, with a median follow-up
of 10 years. Data were collected up to June 2018. We analyzed responses to treatment …

Moxetumomab pasudotox (MP) is an immunotoxin that recently received US Food and Drug
Administration (FDA) approval for the treatment of hairy cell leukemia (HCL) that has failed …

Hematological malignancy like lymphoma originates in lymph tissues and has a propensity
to spread across other organs. Managing such tumors is challenging as conventional …

ABSTRACT Introduction Antibody-drug conjugates (ADCs) are immunoconjugates and
comprise a monoclonal antibody that is chemically attached to a cytotoxic drug (or payload) …

Telomeres compose the end portions of human chromosomes, and their main function is to
protect the genome. In hematological disorders, telomeres are shortened, predisposing to …

Background: Cladribine is an antimetabolite used for the treatment of relapsing–remitting
multiple sclerosis. At present, there are no data available on its use in breastfeeding mothers …

The incidence of lymphoma has rapidly increased over the last 40 years in Japan, following
a trend that is very similar to that of breast cancer. In particular, the relative frequency of …

This atlas presents not only the differential diagnosis but also the detailed morphologic,
immunophenotypic, and especially genetic characteristics of the majority of hematolymphoid …