High-grade serous ovarian cancer (HGSOC) is notoriously known as the “silent killer” of post-
menopausal women as it has an insidious progression and is the deadliest gynaecological …

Women with endometriosis are at increased risk of developing ovarian cancer, specifically
ovarian endometrioid, low-grade serous, and clear-cell adenocarcinoma. An important …

In this study, we investigate mechanisms leading to inflammation and immunoreactivity in
ovarian tumors with homologous recombination deficiency (HRD). BRCA1 loss is found to …

Amplification and overexpression of the MYC oncogene in tumor cells, including ovarian
cancer cells, correlates with poor responses to chemotherapy. As MYC is not directly …

Heterogeneity within the glycocalyx influences cell adhesion mechanics and signaling.
However, the role of specific glycosylation subtypes in influencing cell mechanics via …

Simple Summary High-grade serous ovarian cancer (HGSOC) is the most prevalent type of
ovarian cancer, accounting for 70% of ovarian cancer deaths. This is primarily due to the …

Aldehyde dehydrogenase (ALDH) activity is commonly used as a marker to identify cancer
stem-like cells. The three ALDH1A isoforms have all been individually implicated in cancer …

Adipose tissue, which can provide adipokines and nutrients to tumors, plays a key role in
promoting ovarian cancer metastatic lesions in peritoneal cavity. The adipokine apelin …

The imidazole alkaloid lepidiline A from the root of Lepidium meyenii has a moderate to low
in vitro anticancer effect. Our aim was to extend cytotoxicity investigations against a panel of …

Introduction Ovarian cancer is one of the leading causes of death for women with cancer
worldwide. Energy requirements for tumor growth in epithelial high-grade serous ovarian …