The vitamin D endocrine system is involved in a wide variety of biological processes
including bone metabolism, modulation of the immune response, and regulation of cell …

Osteoporosis is a common disease with a strong genetic component characterized by
reduced bone mass, defects in the microarchitecture of bone tissue, and an increased risk of …

Background Vitamin D was used to treat tuberculosis in the pre-antibiotic era, and its
metabolites induce antimycobacterial immunity in vitro. Clinical trials investigating the effect …

Background Susceptibility to disease after infection by Mycobacterium tuberculosis is
influenced by environmental and host genetic factors. Vitamin D metabolism leads to …

The functional significance of two unlinked human vitamin D receptor (hVDR) gene
polymorphisms was evaluated in twenty human fibroblast cell lines. Genotypes at both a Fok …

A. Historical aspects of VDR structure and function B. The domain structure of the VDR C.
The regulation of gene expression by the VDR IV. Cellular Basis of HVDRR A. Studies in …

Associations have been reported between vitamin D receptor (VDR) gene polymorphisms,
type 1 diabetes, insulin secretion, and the insulin resistance syndrome. As VDR …

Technological advances in the large scale analysis of human genetics have generated
profound insights into possible genetic contributions to chronic diseases including the …

BACKGROUND The vitamin D receptor (VDR) gene represents a strong positional
candidate susceptibility gene for inflammatory bowel disease (IBD). The VDR gene maps to …

Background: Knowledge gaps have contributed to considerable variation among
international dietary recommendations for vitamin D. Objective: We aimed to establish the …