Peroxisome proliferator-activated receptors (PPARs) α, β, and γ are nuclear receptors that
orchestrate the transcriptional regulation of genes involved in a variety of biological …

Abstract Ischemia/reperfusion-(I/R-) induced injury is unavoidable and a major risk factor for
graft failure and acute rejection following kidney transplantation. However, few effective …

Several studies indicate various pharmacological and therapeutic effects of peroxisome
proliferator-activated receptors (PPARs) in different disorders. The current review describes …

Acute kidney injury (AKI) is commonly a result of renal ischemia reperfusion injury (IRI),
which produces clinical complications characterized by the rapid deterioration of renal …

Introduction Rheumatoid arthritis (RA) is a systemic inflammatory autoimmune disease
characterized by joint inflammation and bone damage, that not only restricts patient activity …

Pioglitazone (PIO) is an insulin-sensitizing antidiabetic drug, which normalizes glucose and
lipid metabolism but may provoke heart and liver failure and chronic kidney diseases. Both …

Pseudomonas aeruginosa is a common respiratory pathogen that causes injurious airway
inflammation during acute pneumonia. Peroxisome proliferator-activated receptor (PPAR)-γ …

Objective This review aims to present existing evidence on the impact of pioglitazone, a
thiazolidinedione class anti-diabetic drug, on asthma control and lung function, providing a …