Learning and interpreting the structure of the environment is an innate feature of biological
systems, and is integral to guiding flexible behaviors for evolutionary viability. The concept of …

The medial frontal cortex and adjacent orbitofrontal cortex have been the focus of
investigations of decision-making, behavioral flexibility, and social behavior. We review …

We rely on our long-term memories to guide future behaviors, making it adaptive to prioritize
the retention of goal-relevant, salient information in memory. In this review, we discuss …

We propose that the entirety of the prefrontal cortex (PFC) can be seen as fundamentally
premotor in nature. By this, we mean that the PFC consists of an action abstraction hierarchy …

Humans have the remarkable cognitive capacity to rapidly adapt to changing environments.
Central to this capacity is the ability to form high-level, abstract representations that take …

Learning of adaptive behaviors requires the refinement of coordinated activity across
multiple brain regions. However, how neural communications develop during learning …

Behavioral flexibility depends on our capacity to build and leverage abstract knowledge
about tasks. Recently, two separate lines of research have implicated distinct brain networks …

Neuronal ensembles, defined as groups of neurons displaying recurring patterns of
coordinated activity, represent an intermediate functional level between individual neurons …

Humans and other animals effortlessly generalize prior knowledge to solve novel problems,
by abstracting common structure and mapping it onto new sensorimotor specifics. To …

The brain forms cognitive maps of relational knowledge—an organizing principle thought to
underlie our ability to generalize and make inferences. However, how can a relevant map be …