De novo transcription of DNA is a fundamental requirement for the formation of long-term
memory. It is required during both consolidation and reconsolidation, the posttraining and …

Alzheimer's disease (AD) is a neurodegenerative disease with unknown pathogenesis and
complex pathological manifestations. At present, a large number of studies on targeted …

Genome-wide association studies (GWAS) of psychiatric disorders have identified multiple
genetic associations with such disorders, but better methods are needed to derive the …

Understanding the underlying mechanisms of memory formation and maintenance has been
a major goal in the field of neuroscience. Memory formation and maintenance are tightly …

In the past few decades, the field of neuroepigenetics has investigated how the brain
encodes information to form long-lasting memories that lead to stable changes in behaviour …

Epigenetic aberration is implicated in aging and neurodegeneration. Using postmortem
tissues from patients with Alzheimer's disease (AD) and AD mouse models, we have found …

The influence of diet and environment on human health has been known since ages. Plant-
derived natural bioactive compounds (phytochemicals) have acquired an important role in …

Gene expression and regulation is an important sculptor of the behavior of organisms.
Epigenetic mechanisms regulate gene expression not by altering the genetic alphabet but …

The growing list of mutations implicated in monogenic disorders of the developing brain
includes at least seven genes (ARX, CUL4B, KDM5A, KDM5C, KMT2A, KMT2C, KMT2D) …

Major Depressive Disorder (MDD) entails a multifactorial disorder of rising prevalence.
Nearly 280 million people suffer from this leading cause of disability in the world. Moreover …