The question of how the neural and immune systems interact in host defense is important,
integrating a system that senses the whole body with one that protects. Understanding the …

Neuroplastic changes in the neuronal networks involving the trigeminal ganglion (TG),
trigeminal spinal subnucleus caudalis (Vc), and upper cervical spinal cord (C1/C2) are …

Introduction Neuropathic pain is a debilitating condition. The importance of neuroimmune
interactions in neuropathic pain has been evidenced by the involvement of different immune …

Identification of the key ingredients and essential processes required to achieve perfect
tissue regeneration in humans has so far remained elusive. Injury in vertebrates induces an …

Nerve injury is associated with microvascular disturbance; however, the role of the vascular
system has not been well characterized in the context of neuropathic pain. Furthermore …

The blood-nerve barrier (BNB) is a selectively permeable barrier that creates an
immunologically and biochemically privileged space for peripheral axons and supporting …

The intricate interactions between neurons, glial, and inflammatory cells within peripheral
ganglia are physiologically important, but not well explored. Here, we show that adult dorsal …

Obesity is a significant health concern as a result of poor-quality diet, for example, high-fat
diet (HFD). Although multiple biological and molecular changes have been identified to …

Neuropathic pain pathogenesis is not only confined to changes in the activity of neuronal
systems, but also involves neuro-immune interactions mediated by inflammatory cytokines …

Neuropathic pain resulting from peripheral nerve injury involves many persistent
neuroinflammatory processes including inflammatory chemokines that control leukocyte …