Myricetin-loaded SBA-15 silica nanoparticles for enhanced management of pyrexia, pain, and inflammation through modulation of MAPK/NF-κB and COX-2/PGE-2 …

ZA El-Gendy, NM Ammar, AM Kassem, MS Attia… - International journal of …, 2024 - Elsevier
Myricetin (MYR) is a natural flavonoid that has several biological functions. However, some
of its beneficial effects are diminished due to low water solubility, stability, and …

Optimisation of albendazole delivery and assessment of anticancer potential in hepatocellular carcinoma (HepG2 cells) using surface modified nanostructured lipid …

W Anwar, AM Kassem, A Salama… - Journal of …, 2025 - Taylor & Francis
This study evaluated albendazole (ABZ) nanostructured lipid carriers (NLCs) for
hepatocellular carcinoma treatment. ABZ-NLCs were prepared using emulsification …

[HTML][HTML] Development and Characterization of In Situ Gelling Nasal Cilostazol Spanlastics

M Salamah, M Budai-Szűcs, B Sipos, B Volk, G Katona… - Gels, 2025 - mdpi.com
Cilostazol (CIL), a BCS class II antiplatelet aggregation and vasodilator agent, is used for
cerebrovascular diseases to minimize blood–brain barrier dysfunction, white matter-lesion …

[HTML][HTML] Spanlastic Nano-Vesicles: A Novel Approach to Improve the Dissolution, Bioavailability, and Pharmacokinetic Behavior of Famotidine

HI Almohamady, Y Mortagi, S Gad, S Zaitone… - …, 2024 - pmc.ncbi.nlm.nih.gov
Background/Objectives: Drugs exhibiting poor aqueous solubility present a challenge to
efficient delivery to the site of action. Spanlastics (a nano, surfactant-based drug delivery …

Evaluation of Drug Permeation Enhancement by Using In Vitro and Ex Vivo Models

JD Steyn, A Haasbroek-Pheiffer, W Pheiffer, M Weyers… - Pharmaceuticals, 2025 - mdpi.com
Drugs administered by means of extravascular routes of drug administration must be
absorbed into the systemic circulation, which involves the movement of the drug molecules …