Functional evaluation of peripheral nerve regeneration in the rat: walking track analysis

ASP Varejão, MF Meek, AJA Ferreira… - Journal of neuroscience …, 2001 - Elsevier
The experimental model of choice for many peripheral nerve investigators is the rat. Walking
track analysis is a useful tool in the evaluation of functional peripheral nerve recovery in the …

The genetic mediation of individual differences in sensitivity to pain and its inhibition

JS Mogil - Proceedings of the National Academy of …, 1999 - National Acad Sciences
The underlying bases of the considerable interindividual variability in pain-related traits are
starting to be revealed. Although the relative importance of genes versus experience in …

Processed allografts and type I collagen conduits for repair of peripheral nerve gaps

EL Whitlock, SH Tuffaha, JP Luciano… - Muscle & Nerve …, 2009 - Wiley Online Library
Autografting is the gold standard in the repair of peripheral nerve injuries that are not
amenable to end‐to‐end coaptation. However, because autografts result in donor‐site …

Methods for the experimental functional assessment of rat sciatic nerve regeneration

ASP Varejão, P Melo-Pinto, MF Meek… - Neurological …, 2004 - Taylor & Francis
In experimental peripheral nerve studies, the rat sciatic nerve model is widely used to
examine functional changes after different surgical repairs or pharmacological treatments …

Collagen-GAG substrate enhances the quality of nerve regeneration through collagen tubes up to level of autograft

LJ Chamberlain, IV Yannas, HP Hsu, G Strichartz… - Experimental …, 1998 - Elsevier
Peripheral nerve regeneration was studied across a tubulated 10-mm gap in the rat sciatic
nerve using histomorphometry and electrophysiological measurements of A-fiber, B-fiber …

Sciatic nerve injury: a simple and subtle model for investigating many aspects of nervous system damage and recovery

LE Savastano, SR Laurito, MR Fitt… - Journal of neuroscience …, 2014 - Elsevier
Sciatic nerve injury has been used for over a century to investigate the process of nerve
damage, to assess the absolute and relative capacity of the central and peripheral nervous …

Axotomy- and Autotomy-Induced Changes in Ca2+and K+ Channel Currents of Rat Dorsal Root Ganglion Neurons

FA Abdulla, PA Smith - Journal of neurophysiology, 2001 - journals.physiology.org
Sciatic nerve section (axotomy) increases the excitability of rat dorsal root ganglion (DRG)
neurons. The changes in Ca2+ currents, K+ currents, Ca2+-sensitive K+ current, and …

Biopolymer-nanotube nerve guidance conduit drug delivery for peripheral nerve regeneration: In vivo structural and functional assessment

OS Manoukian, S Rudraiah, MR Arul, JM Bartley… - Bioactive Materials, 2021 - Elsevier
Peripheral nerve injuries account for roughly 3% of all trauma patients with over 900,000
repair procedures annually in the US. Of all extremity peripheral nerve injuries, 51% require …

Near‐terminus axonal structure and function following rat sciatic nerve regeneration through a collagen‐GAG matrix in a ten‐millimeter gap

LJ Chamberlain, IV Yannas, HP Hsu… - Journal of …, 2000 - Wiley Online Library
The objectives of this study were to evaluate the regenerated axon structure at near‐terminal
locations in the peroneal and tibial branches 1 year following implantation of several tubular …

Walking track analysis: an assessment method for functional recovery after sciatic nerve injury in the rat

L Sarikcioglu, BM Demirel, A Utuk - Folia morphologica, 2009 - journals.viamedica.pl
Walking track analysis was first described by de Medinaceli et al. This technique has been
significantly modified to provide methods of indexing nerve function that are more valid …