Early imaging studies in temporal lobe epilepsy (TLE) focused on the search for mesial
temporal sclerosis, as its surgical removal results in clinically meaningful improvement in …

Hippocampal sclerosis (HS) is the most frequent histopathology encountered in patients with
drug‐resistant temporal lobe epilepsy (TLE). Over the past decades, various attempts have …

Epilepsy is a prevalent chronic condition affecting about 50 million people worldwide. A third
of patients suffer from seizures unresponsive to medication. Uncontrolled seizures damage …

BACKGROUND: The promise of Alzheimer's disease biomarkers has led to their
incorporation in new diagnostic criteria and in therapeutic trials; however, significant barriers …

Abstract Study Objectives: Despite compelling evidence from animal studies indicating
hippocampal subfield-specific vulnerability to poor sleep quality and related cognitive …

Objective In temporal lobe epilepsy (TLE), although hippocampal atrophy lateralizes the
focus, the value of magnetic resonance imaging (MRI) to predict postsurgical outcome is …

Objective: Evidence for disease progression in the mesiotemporal lobe is mainly derived
from global volumetry of the hippocampus. In this study, we tracked progressive structural …

Objectives: The significance of hippocampal sleep spindles and their relation to epileptic
activity is still a matter of controversy. Hippocampal spindles have been considered a …

Temporal lobe epilepsy (TLE) is the most frequent drug-resistant epilepsy in adults and
commonly associated with variable degrees of mesiotemporal atrophy on magnetic …

In drug‐resistant temporal lobe epilepsy (TLE), MRI studies have shown consistent
mesiotemporal and neocortical structural alterations when comparing patients to healthy …