[HTML][HTML] Gender differences in autoimmune disease

ST Ngo, FJ Steyn, PA McCombe - Frontiers in neuroendocrinology, 2014 - Elsevier
Autoimmune diseases are a range of diseases in which the immune response to self-
antigens results in damage or dysfunction of tissues. Autoimmune diseases can be systemic …

Epidemiology of multiple sclerosis

J Howard, S Trevick, DS Younger - Neurologic clinics, 2016 - neurologic.theclinics.com
The Americas In 2007, Poser and Brinar 1 noted that published prevalence rates of multiple
sclerosis (MS) could be misleading with the reliance on clinical information and brain MRI …

Sex and gender issues in multiple sclerosis

HF Harbo, R Gold, M Tintoré - Therapeutic advances in …, 2013 - journals.sagepub.com
Multiple sclerosis (MS) is universally found to be more prevalent in women than men. This
has led to extensive studies of differences in the immune system or nervous system between …

The changing demographic pattern of multiple sclerosis epidemiology

N Koch-Henriksen, PS Sørensen - The Lancet Neurology, 2010 - thelancet.com
The uneven distribution of multiple sclerosis (MS) across populations can be attributed to
differences in genes and the environment and their interaction. Prevalence and incidence …

Multiple sclerosis: risk factors, prodromes, and potential causal pathways

SV Ramagopalan, R Dobson, UC Meier… - The Lancet …, 2010 - thelancet.com
Multiple sclerosis (MS) is a common, complex neurological disease. The precise aetiology of
MS is not yet known, although epidemiological data indicate that both genetic and …

Epigenetics and transgenerational transfer: a physiological perspective

DH Ho, WW Burggren - Journal of Experimental Biology, 2010 - journals.biologists.com
Epigenetics, the transgenerational transfer of phenotypic characters without modification of
gene sequence, is a burgeoning area of study in many disciplines of biology. However, the …

Environmental factors and their timing in adult-onset multiple sclerosis

AE Handel, G Giovannoni, GC Ebers… - Nature Reviews …, 2010 - nature.com
Multiple sclerosis (MS) is a common, complex neurological disease. Epidemiological data
implicate both genetic and environmental factors in the etiology of MS, with various factors …

Sex-specific parent-of-origin allelic expression in the mouse brain

C Gregg, J Zhang, JE Butler, D Haig, C Dulac - Science, 2010 - science.org
Genomic imprinting results in preferential gene expression from paternally versus maternally
inherited chromosomes. We used a genome-wide approach to uncover sex-specific parent …

Modest familial risks for multiple sclerosis: a registry-based study of the population of Sweden

H Westerlind, R Ramanujam, D Uvehag… - Brain, 2014 - academic.oup.com
Data on familial recurrence rates of complex diseases such as multiple sclerosis give
important hints to aetiological factors such as the importance of genes and environment. By …

Epigenetics: molecular mechanisms and implications for disease

AE Handel, GC Ebers, SV Ramagopalan - Trends in molecular medicine, 2010 - cell.com
Epigenetics is rising to prominence in biology as a mechanism by which environmental
factors have intermediate-term effects on gene expression without changing the underlying …