[HTML][HTML] Self-assembling drug formulations with tunable permeability and biodegradability
G Gaynanova, L Vasileva, R Kashapov, D Kuznetsova… - Molecules, 2021 - mdpi.com
This review focuses on key topics in the field of drug delivery related to the design of
nanocarriers answering the biomedicine criteria, including biocompatibility, biodegradability …
nanocarriers answering the biomedicine criteria, including biocompatibility, biodegradability …
[HTML][HTML] Nanotechnology based solutions for anti-leishmanial impediments: a detailed insight
As a neglected tropical disease, Leishmaniasis is significantly instigating morbidity and
mortality across the globe. Its clinical spectrum varies from ulcerative cutaneous lesions to …
mortality across the globe. Its clinical spectrum varies from ulcerative cutaneous lesions to …
Cilostazol-loaded solid lipid nanoparticles: Bioavailability and safety evaluation in an animal model
Cilostazol (CLZ) is an antiplatelet agent with limited solubility (∼ 6 μg/ml at 25° C), poor
absorption and low oral bioavailability. In this study, solid lipid nanoparticles (SLNs) were …
absorption and low oral bioavailability. In this study, solid lipid nanoparticles (SLNs) were …
Development, Characterization, and Evaluation of SLN‐Loaded Thermoresponsive Hydrogel System of Topotecan as Biological Macromolecule for Colorectal …
Background. Chemotherapeutic drugs cause severe toxicities if administered unprotected,
without proper targeting, and controlled release. In this study, we developed topotecan‐(TPT …
without proper targeting, and controlled release. In this study, we developed topotecan‐(TPT …
Hyaluronan-modified transfersomes based hydrogel for enhanced transdermal delivery of indomethacin
M Yuan, J Niu, Q Xiao, H Ya, Y Zhang, Y Fan, L Li… - Drug …, 2022 - Taylor & Francis
Hyaluronic acid (HA), as a hygroscopic and biocompatible molecule, has displayed unique
permeation enhancement in transdermal delivery systems. Hence, indomethacin (IND) was …
permeation enhancement in transdermal delivery systems. Hence, indomethacin (IND) was …
Macrophage targeting of nitazoxanide-loaded transethosomal gel in cutaneous leishmaniasis
Topical delivery is preferable over systemic delivery for cutaneous leishmaniasis, because
of its easy administration, reduced systemic adverse effects and low cost. Nitazoxanide …
of its easy administration, reduced systemic adverse effects and low cost. Nitazoxanide …
Co-delivery of amphotericin B and pentamidine loaded niosomal gel for the treatment of Cutaneous leishmaniasis
Topical drug delivery is preferable route over systemic delivery in case of Cutaneous
leishmaniasis (CL). Among the available agents, amphotericin B (AmB) and pentamidine …
leishmaniasis (CL). Among the available agents, amphotericin B (AmB) and pentamidine …
[HTML][HTML] Preparation, characterization and permeation study of topical gel loaded with transfersomes containing asiatic acid
SAT Opatha, V Titapiwatanakun, K Boonpisutiinant… - Molecules, 2022 - mdpi.com
The objective of this study is to investigate the in vitro permeation of asiatic acid (AA) in the
form of a topical gel after entrapment in transfersomes by Franz diffusion cells …
form of a topical gel after entrapment in transfersomes by Franz diffusion cells …
[HTML][HTML] A cutback in Imiquimod cutaneous toxicity; comparative cutaneous toxicity analysis of Imiquimod nanotransethosomal gel with 5% marketed cream on the …
Herein, Imiquimod (IMQ) was incorporated in nanotransethosomes (nTES) to develop the
IMQ-nTES nano-drug delivery system. IMQ-nTES was optimized using 23 factorial design …
IMQ-nTES nano-drug delivery system. IMQ-nTES was optimized using 23 factorial design …
Statistical optimization of co-loaded rifampicin and pentamidine polymeric nanoparticles for the treatment of cutaneous leishmaniasis
Topical drug delivery against cutaneous leishmaniasis (CL) serves as an effective alternate
approach to improve efficacy and reduce systemic adverse effects. The purpose of this study …
approach to improve efficacy and reduce systemic adverse effects. The purpose of this study …