Spinal cord stimulation (SCS) as an evidence‐based interventional treatment has been
used and approved for clinical use in a variety of pathological states including peripheral …

Chronic neuropathic pain (CNP) refers to pain that lasts for more than three months due to a
disease or an injury to the somatosensory nervous system. The incidence of CNP has been …

Purpose: Abundant retinal microRNA-183 cluster (miR-183C) has been reported to be a key
player in photoreceptor development and functionality in mice. However, whether there is a …

The major obstacle in developing new treatment strategies for refractory epilepsy is the
complexity and poor understanding of its mechanisms. Utilizing the model of lamotrigine …

Introduction Inflammatory bowel disease (IBD) is a chronic disease involving multiple genes,
and the current available targeted drugs for IBD only deliver moderate efficacy. Whether …

Abstract Ethnopharmacology relevance Zanthoxylum bungeanum Maxim.(Z. bungeanum), a
member of the Rutaceae family, has a rich history of traditional use in Asia for treating …

Double knockout of miR-183 and miR-96 results in retinal degeneration in mice; however,
single knockout of miR-96 leads to developmental delay but not substantial retinal …

目的三叉神经痛(trigeminal neuralgia， TN) 是一种严重的慢性神经病理性疼痛，
主要影响三叉神经分布区域， 临床治疗效果不佳。 TN 的治疗方法众多， 但目前临床上主要是 …

Abstract Neuropathic pain affects 7-10% of the global population, and one of its
characteristics is sensitization of somatosensory nervous system. Altered expression of ion …

Neuropathic pain (NP) induced by spinal cord injury (SCI) often causes long-term
disturbance for patients, but the mechanisms behind remains unclear. Here, our study …