In this second part of our review article on the preferred screw sense and interconversion of
peptide helices, we discuss the most significant computational and experimental data …

This review summarizes recent developments in conjugation techniques for the synthesis of
cell-penetrating peptide (CPP)–drug conjugates targeting cancer cells. We will focus on …

α-Aminoisobutyric acid (Aib) is a Cα-tetrasubstituted amino acid that strongly favors helical
structure. Most of the conformational trends established for Aib-rich peptides have been …

Abstract Models for the 310‐helix/coil and π‐helix/coil equilibria have been derived. The
theory is based on classifying residues into helical or nonhelical (coil) conformations …

Abstract Model peptides based on‐(Aib‐Ala) n‐, and (Aib) n‐Leu‐(Aib) 2 sequences, which
have varying amounts of 310‐helical character, were studied by use of vibrational and …

Helical peptides that can intervene and disrupt therapeutically important protein–protein
interactions are attractive drug targets. In order to develop a general strategy for developing …

The-helix and the 3io helix are two common constituents of protein architecture.
Spectroscopy and crystallography indicate that short peptides containing alanine tend to …

Due to the difficulties in experimentally differentiating between thea-and 3io-helical
conformations in solution, isolated helical peptides have beenassumed to be in the-helical …

Short-range interactions dominate in determining the conformational preferences of the
amino acid residues in proteins, and a variety of procedures (based on this concept) have …

The shortest helices (three-length 310 and four-length α), most abundant among helices of
different lengths, have been analyzed from a database of protein structures. A characteristic …