Neurodegenerative diseases are a spectrum of chronic, debilitating disorders characterised
by the progressive degeneration and death of neurons. Mitochondrial dysfunction has been …

Simple Summary Multielectrode array technology allows researchers to record the
spontaneous firing activity of cultured neurons over a period of multiple weeks or months …

Neuronal models are a crucial tool in neuroscientific research, helping to elucidate the
molecular and cellular processes involved in disorders of the nervous system. Adapting …

Micro-electrode arrays (MEAs) are increasingly used to characterize neuronal network
activity of human induced pluripotent stem cell (hiPSC)-derived neurons. Despite their gain …

The correct subcellular distribution of proteins establishes the complex morphology and
function of neurons. Fluorescence microscopy techniques are invaluable to investigate …

Primary rodent neurons and immortalised cell lines have overwhelmingly been used for in
vitro studies of traumatic injury to peripheral and central neurons, but have some limitations …

Despite the fact that the phenomenon of bursting activity is important for functioning of living
neural networks, the mechanisms of its origin are still not clear. In this paper, we propose a …

Multi-electrode arrays, both active or passive, emerged as ideal technologies to unveil
intricated electrophysiological dynamics of cells and tissues. Active MEAs, designed using …

Attention-deficit hyperactivity disorder (ADHD) is a common childhood-onset psychiatric
disorder characterized by inattention, impulsivity and hyperactivity. ADHD exhibits …

We examined neural network ontogeny using microelectrode array (MEA) recordings made
in multiwell MEA (mwMEA) plates over the first 12 days in vitro (DIV). In primary cortical …