14-3-3 proteins were the first signaling molecules to be identified as discrete phosphoserine/
threonine binding modules. This family of proteins, which includes seven isotypes in human …

The olfactory nervous system of insects and mammals exhibits many similarities, which
suggests that the mechanisms for olfactory learning may be shared. Molecular genetic …

14-3-3 proteins exert an extraordinarily widespread influence on cellular processes in all
eukaryotes. They operate by binding to specific phosphorylated sites on diverse target …

The last 30 years have witnessed tremendous progress in elucidating the basic mechanisms
underlying a simple form of olfactory learning and memory in Drosophila. The application of …

The rich behavioral repertoire that Drosophila use to navigate in their natural environment
suggests that flies can use memories to inform decisions. Development of paradigms to …

Mutations in the neuronal-specific microtubule-binding protein TAU are associated with
several dementias and neurodegenerative diseases. However, the effects of elevated TAU …

J. Neurochem.(2010) 113, 1577–1588. Abstract Decreased cognitive performance reduces
independence and quality of life for aging individuals. Healthy brain aging does not involve …

14–3–3 genes encode a ubiquitous family of highly conserved eukaryotic proteins from fungi
to humans and plants with several molecular and cellular functions. Most notably, 14–3–3 …

Among the first reported functions of 14-3-3 proteins was the regulation of tyrosine
hydroxylase (TH) activity suggesting a possible involvement of 14-3-3 proteins in …

Transthyretin (TTR) is a protein that binds and distributes thyroid hormones (TH s). TTR
synthesised in the liver is secreted into the bloodstream and distributes TH s around the …