About twenty years ago, the functional lipid raft model of the plasma membrane was
published. It took into account decades of research showing that cellular membranes are not …

To execute their many vital functions, cell membranes are highly organized. Here, we review
how membrane structure shapes signal transduction across membranes. Recent …

The plasma membrane has a highly asymmetric distribution of lipids and contains dynamic
nanodomains many of which are liquid entities surrounded by a second, slightly different …

The scientific premise, design, and structure-function analysis of chemical-based muscle
membrane stabilizing block copolymers are reviewed here for applications in striated …

Small-angle X-ray and neutron scattering are well-established, non-invasive experimental
techniques to interrogate global structural properties of biological membrane mimicking …

A lipid membrane undergoes a phase transition from fluid to gel phase upon changing
external thermodynamic conditions, such as decreasing temperature and increasing …

Saturated and unsaturated phospholipids (PLs) can segregate into lateral domains. The
preference of cholesterol for saturated acyl chains over monounsaturated, and especially …

Serotonin is an endogenous neurotransmitter involved in both physiological and
pathophysiological processes. Traditionally, serotonin acts as a ligand for G protein-coupled …

The ordered environment of cholesterol-rich membrane nanodomains is thought to exclude
many transmembrane (TM) proteins. Nevertheless, some multispan helical transmembrane …

Cholesterol is a key component of eukaryotic membranes, but its role in cellular biology in
general and in lipid rafts in particular remains controversial. Model membranes are used …