Lymphedema: Pathophysiology and clinical manifestations

AA Grada, TJ Phillips - Journal of the American Academy of Dermatology, 2017 - Elsevier
Lymphedema is a localized form of tissue swelling resulting from excessive retention of
lymphatic fluid in the interstitial compartment and caused by impaired lymphatic drainage …

Primary lymphoedema

P Brouillard, MH Witte, RP Erickson… - Nature reviews Disease …, 2021 - nature.com
Lymphoedema is the swelling of one or several parts of the body owing to lymph
accumulation in the extracellular space. It is often chronic, worsens if untreated, predisposes …

New developments in clinical aspects of lymphatic disease

PS Mortimer, SG Rockson - The Journal of clinical …, 2014 - Am Soc Clin Investig
The lymphatic system is fundamentally important to cardiovascular disease, infection and
immunity, cancer, and probably obesity—the four major challenges in healthcare in the 21st …

The earliest finding of indocyanine green lymphography in asymptomatic limbs of lower extremity lymphedema patients secondary to cancer treatment: the modified …

T Yamamoto, N Matsuda, K Doi, A Oshima… - Plastic and …, 2011 - journals.lww.com
Background: Early diagnosis and treatment are as important for management of secondary
lymphedema following cancer treatment as in primary cancer treatment. Indocyanine green …

The American Venous Forum, American Vein and Lymphatic Society and the Society for Vascular Medicine expert opinion consensus on lymphedema diagnosis and …

F Lurie, RD Malgor, T Carman, SM Dean… - …, 2022 - journals.sagepub.com
Background Lymphedema imposes a significant economic and social burden in modern
societies. Controversies about its risk factors, diagnosis, and treatment permeate the …

Penicillin to prevent recurrent leg cellulitis

KS Thomas, AM Crook, AJ Nunn… - New England journal …, 2013 - Mass Medical Soc
Background Cellulitis of the leg is a common bacterial infection of the skin and underlying
tissue. We compared prophylactic low-dose penicillin with placebo for the prevention of …

Lower limb cellulitis and its mimics: part I. Lower limb cellulitis

JV Hirschmann, GJ Raugi - Journal of the American Academy of …, 2012 - Elsevier
An aging population and obesity have both contributed to a rising incidence of lower limb
cellulitis; the most important predisposing factors include older age, obesity, venous …

Risk factors for nonpurulent leg cellulitis: a systematic review and meta‐analysis

M Quirke, F Ayoub, A McCabe, F Boland… - British Journal of …, 2017 - academic.oup.com
Nonpurulent cellulitis is an acute bacterial infection of the dermal and subdermal tissues that
is not associated with purulent drainage, discharge or abscess. The objectives of this …

Development and physiological functions of the lymphatic system: insights from human genetic studies of primary lymphedema

S Martin-Almedina, PS Mortimer… - Physiological …, 2021 - journals.physiology.org
Primary lymphedema is a long-term (chronic) condition characterized by tissue lymph
retention and swelling that can affect any part of the body, although it usually develops in the …

Interventions for the prevention of recurrent erysipelas and cellulitis

A Dalal, M Eskin‐Schwartz, D Mimouni… - Cochrane Database …, 2017 - cochranelibrary.com
Background Erysipelas and cellulitis (hereafter referred to as' cellulitis') are common
bacterial skin infections usually affecting the lower extremities. Despite their burden of …