Circular RNAs act as miRNA sponges

AC Panda - Circular RNAs: biogenesis and functions, 2018 - Springer
Majority of RNAs expressed in animal cells lack protein-coding ability. Unlike other cellular
RNAs, circular (circ) RNAs include a large family of noncoding (nc) RNAs that lack the 5′ or …

[HTML][HTML] Non-coding RNAs as regulators in epigenetics

JW Wei, K Huang, C Yang… - Oncology reports, 2017 - spandidos-publications.com
Epigenetics is a discipline that studies heritable changes in gene expression that do not
involve altering the DNA sequence. Over the past decade, researchers have shown that …

miRTarBase 2020: updates to the experimentally validated microRNA–target interaction database

HY Huang, YCD Lin, J Li, KY Huang… - Nucleic acids …, 2020 - academic.oup.com
MicroRNAs (miRNAs) are small non-coding RNAs (typically consisting of 18–25
nucleotides) that negatively control expression of target genes at the post-transcriptional …

miRTarBase update 2018: a resource for experimentally validated microRNA-target interactions

CH Chou, S Shrestha, CD Yang… - Nucleic acids …, 2018 - academic.oup.com
MicroRNAs (miRNAs) are small non-coding RNAs of∼ 22 nucleotides that are involved in
negative regulation of mRNA at the post-transcriptional level. Previously, we developed …

miRTarBase 2016: updates to the experimentally validated miRNA-target interactions database

CH Chou, NW Chang, S Shrestha, SD Hsu… - Nucleic acids …, 2016 - academic.oup.com
MicroRNAs (miRNAs) are small non-coding RNAs of approximately 22 nucleotides, which
negatively regulate the gene expression at the post-transcriptional level. This study …

MicroRNA key to angiogenesis regulation: MiRNA biology and therapy

A Tiwari, B Mukherjee, M Dixit - Current cancer drug targets, 2018 - ingentaconnect.com
Angiogenesis is involved in maintaining normal physiological processes like embryonic
development, wound healing, inflammation and reproduction. Pathogenesis of various …

MicroRNA: biogenesis, function and role in cancer

LA MacFarlane, PR Murphy - Current genomics, 2010 - ingentaconnect.com
MicroRNAs are small, highly conserved non-coding RNA molecules involved in the
regulation of gene expression. MicroRNAs are transcribed by RNA polymerases II and III …

[HTML][HTML] miRWalk–database: prediction of possible miRNA binding sites by “walking” the genes of three genomes

H Dweep, C Sticht, P Pandey, N Gretz - Journal of biomedical informatics, 2011 - Elsevier
MicroRNAs are small, non-coding RNA molecules that can complementarily bind to the
mRNA 3′-UTR region to regulate the gene expression by transcriptional repression or …

Identifying miRNAs, targets and functions

B Liu, J Li, MJ Cairns - Briefings in bioinformatics, 2014 - academic.oup.com
Abstract microRNAs (miRNAs) are small endogenous non-coding RNAs that function as the
universal specificity factors in post-transcriptional gene silencing. Discovering miRNAs …

Molecular distinction between physiological and pathological cardiac hypertrophy: experimental findings and therapeutic strategies

BC Bernardo, KL Weeks, L Pretorius… - Pharmacology & …, 2010 - Elsevier
Cardiac hypertrophy can be defined as an increase in heart mass. Pathological cardiac
hypertrophy (heart growth that occurs in settings of disease, eg hypertension) is a key risk …