Intracellular mRNA transport and localized translation

S Das, M Vera, V Gandin, RH Singer… - Nature reviews Molecular …, 2021 - nature.com
Fine-tuning cellular physiology in response to intracellular and environmental cues requires
precise temporal and spatial control of gene expression. High-resolution imaging …

[HTML][HTML] mRNA localization: gene expression in the spatial dimension

KC Martin, A Ephrussi - Cell, 2009 - cell.com
The localization of mRNAs to subcellular compartments provides a mechanism for
regulating gene expression with exquisite temporal and spatial control. Recent studies …

DMS-MaPseq for genome-wide or targeted RNA structure probing in vivo

M Zubradt, P Gupta, S Persad, AM Lambowitz… - Nature …, 2017 - nature.com
Coupling of structure-specific in vivo chemical modification to next-generation sequencing is
transforming RNA secondary structure studies in living cells. The dominant strategy for …

Genome-wide probing of RNA structure reveals active unfolding of mRNA structures in vivo

S Rouskin, M Zubradt, S Washietl, M Kellis… - Nature, 2014 - nature.com
RNA has a dual role as an informational molecule and a direct effector of biological tasks.
The latter function is enabled by RNA's ability to adopt complex secondary and tertiary folds …

m6A and YTHDF proteins contribute to the localization of select neuronal mRNAs

MN Flamand, KD Meyer - Nucleic Acids Research, 2022 - academic.oup.com
The transport of mRNAs to distal subcellular compartments is an important component of
spatial gene expression control in neurons. However, the mechanisms that control mRNA …

[HTML][HTML] Remote control of gene function by local translation

H Jung, CG Gkogkas, N Sonenberg, CE Holt - Cell, 2014 - cell.com
The subcellular position of a protein is a key determinant of its function. Mounting evidence
indicates that RNA localization, where specific mRNAs are transported subcellularly and …

Moving messages: the intracellular localization of mRNAs

D St Johnston - Nature reviews Molecular cell biology, 2005 - nature.com
Abstract mRNA localization is a common mechanism for targeting proteins to regions of the
cell where they are required. It has an essential role in localizing cytoplasmic determinants …

mRNA localization: message on the move

RP Jansen - Nature reviews Molecular cell biology, 2001 - nature.com
Cytoplasmic messenger RNA localization is a key post-transcriptional mechanism of
establishing spatially restricted protein synthesis. The characterization of cis-acting signals …

Dynamics of a mobile RNA of potato involved in a long-distance signaling pathway

AK Banerjee, M Chatterjee, Y Yu, SG Suh… - The Plant …, 2006 - academic.oup.com
BEL1-like transcription factors interact with Knotted1 types to regulate numerous
developmental processes. In potato (Solanum tuberosum), the BEL1 transcription factor St …

[HTML][HTML] Mechanisms of subcellular mRNA localization

M Kloc, NR Zearfoss, LD Etkin - Cell, 2002 - cell.com
Localization of RNA is a widespread and efficient way to target gene products to a specific
region of a cell or embryo. This strategy of posttranscriptional gene regulation utilizes a …