Top value platform chemicals: bio-based production of organic acids

J Becker, A Lange, J Fabarius, C Wittmann - Current opinion in …, 2015 - Elsevier
Highlights•High-value organic acids range from carbon-two to carbon-six molecules.•
Engineered microbial cells reach titers of more than 200 g/L of organic acids.•Production …

Transformation of biomass into commodity chemicals using enzymes or cells

AJJ Straathof - Chemical reviews, 2014 - ACS Publications
Biomass can be classified broadly as all the matter on the earth's surface of recent biological
origin. 1 Biomass includes plant materials such as trees, grasses, agricultural crops, algal …

Progress in Metabolic Engineering of Saccharomyces cerevisiae

E Nevoigt - Microbiology and Molecular Biology Reviews, 2008 - Am Soc Microbiol
The traditional use of the yeast Saccharomyces cerevisiae in alcoholic fermentation has,
over time, resulted in substantial accumulated knowledge concerning genetics, physiology …

Biotechnological applications of Yarrowia lipolytica: past, present and future

HH Liu, XJ Ji, H Huang - Biotechnology Advances, 2015 - Elsevier
Non-conventional yeasts have attracted increasing interest due to their biochemical
characteristics and potential applications. Yarrowia lipolytica is a non-conventional yeast …

Biotechnological routes based on lactic acid production from biomass

C Gao, C Ma, P Xu - Biotechnology advances, 2011 - Elsevier
Lactic acid, the most important hydroxycarboxylic acid, is now commercially produced by the
fermentation of sugars present in biomass. In addition to its use in the synthesis of …

Debaryomyces hansenii — an extremophilic yeast with biotechnological potential

U Breuer, H Harms - Yeast, 2006 - Wiley Online Library
We illuminate the ecological, physiological and genetic characteristics of the yeast
Debaryomyces hansenii in the view of our belief that this metabolically versatile, non …

Engineering Escherichia coli for efficient conversion of glucose to pyruvate

TB Causey, KT Shanmugam… - Proceedings of the …, 2004 - National Acad Sciences
Escherichia coli TC44, a derivative of W3110, was engineered for the production of pyruvate
from glucose by combining mutations to minimize ATP yield, cell growth, and CO2 …

Glycerol as a promising substrate for Yarrowia lipolytica biotechnological applications

A Rywińska, P Juszczyk, M Wojtatowicz, M Robak… - Biomass and …, 2013 - Elsevier
Unconventional and nonpathogenic Yarrowia lipolytica yeast has been addressed in
various studies conducted in many research centers, and in recent years has been …

Directed Evolution of Pyruvate Decarboxylase-Negative Saccharomyces cerevisiae, Yielding a C2-Independent, Glucose-Tolerant, and Pyruvate-Hyperproducing …

AJA Van Maris, JMA Geertman… - Applied and …, 2004 - Am Soc Microbiol
The absence of alcoholic fermentation makes pyruvate decarboxylase-negative (Pdc−)
strains of Saccharomyces cerevisiae an interesting platform for further metabolic …

Ethanol production by selected intestinal microorganisms and lactic acid bacteria growing under different nutritional conditions

FMF Elshaghabee, W Bockelmann, D Meske… - Frontiers in …, 2016 - frontiersin.org
To gain some specific insight into the roles microorganisms might play in non-alcoholic fatty
liver disease (NAFLD), some intestinal and lactic acid bacteria and one yeast (Anaerostipes …