Aims The expression of GADD153 (growth arrest and DNA damage-inducible gene 153), an
apoptosis-regulated gene, increases during endoplasmic reticulum (ER) stress. How …

Afferent and efferent cardiac neurotransmission via the cardiac nerves intricately modulates
nearly all physiological functions of the heart (chronotropy, dromotropy, lusitropy, and …

Background Catheter-based renal denervation has significantly reduced blood pressure in
previous studies. Following a positive pilot trial, the SPYRAL HTN-OFF MED (SPYRAL …

Background Early studies suggest that radiofrequency-based renal denervation reduces
blood pressure in patients with moderate hypertension. We investigated whether an …

La tarea de elaboración de GPC incluye la creación de herramientas educativas y
programas de implementación de las recomendaciones. Para su implementación, se …

Aims Several studies and registries have demonstrated sustained reductions in blood
pressure (BP) after renal denervation (RDN). The long-term safety and efficacy after RDN in …

Abstract Aims The SYMPLICITY HTN-3 randomized, blinded, sham-controlled trial confirmed
the safety of renal denervation (RDN), but did not meet its primary efficacy endpoint. Prior …

Background Conflicting blood pressure-lowering effects of catheter-based renal artery
denervation have been reported in patients with resistant hypertension. We compared the …

Background: Although renal sympathetic denervation therapy has shown promising results
in patients with resistant hypertension, the human anatomy of peri-arterial renal nerves is …

Hypertension is the most common modifiable risk factor for cardiovascular disease and
death, and lowering blood pressure with antihypertensive drugs reduces target organ …