Epigenetic regulation in neurodegenerative diseases

A Berson, R Nativio, SL Berger, NM Bonini - Trends in neurosciences, 2018 - cell.com
Mechanisms of epigenetic regulation, including DNA methylation, chromatin remodeling,
and histone post-translational modifications, are involved in multiple aspects of neuronal …

Gestational hypoxia and developmental plasticity

CA Ducsay, R Goyal, WJ Pearce… - Physiological …, 2018 - journals.physiology.org
Hypoxia is one of the most common and severe challenges to the maintenance of
homeostasis. Oxygen sensing is a property of all tissues, and the response to hypoxia is …

Patterns of reliability: assessing the reproducibility and integrity of DNA methylation measurement

K Sugden, EJ Hannon, L Arseneault, DW Belsky… - Patterns, 2020 - cell.com
DNA methylation plays an important role in both normal human development and risk of
disease. The most utilized method of assessing DNA methylation uses BeadChips …

[HTML][HTML] The gut-brain connection: Exploring the influence of the gut microbiota on neuroplasticity and neurodevelopmental disorders

F Damiani, S Cornuti, P Tognini - Neuropharmacology, 2023 - Elsevier
Neuroplasticity refers to the ability of brain circuits to reorganize and change the properties
of the network, resulting in alterations in brain function and behavior. It is traditionally …

Genome-wide DNA methylation profiling identifies convergent molecular signatures associated with idiopathic and syndromic autism in post-mortem human brain …

CCY Wong, RG Smith, E Hannon… - Human molecular …, 2019 - academic.oup.com
Autism spectrum disorder (ASD) encompasses a collection of complex neuropsychiatric
disorders characterized by deficits in social functioning, communication and repetitive …

Alcohol as an early life stressor: Epigenetics, metabolic, neuroendocrine and neurobehavioral implications

S Ciafrè, G Ferraguti, A Greco, A Polimeni… - Neuroscience & …, 2020 - Elsevier
Ethanol exposure during gestation is an early life stressor that profoundly dysregulates
structure and functions of the embryonal nervous system, altering the cognitive and …

Genetics of schizophrenia: historical insights and prevailing evidence

J Van de Leemput, JL Hess, SJ Glatt, MT Tsuang - Advances in genetics, 2016 - Elsevier
Abstract Schizophrenia's (SZ's) heritability and familial transmission have been known for
several decades; however, despite the clear evidence for a genetic component, it has been …

Retrotransposon-induced mosaicism in the neural genome

GO Bodea, EGZ McKelvey, GJ Faulkner - Open Biology, 2018 - royalsocietypublishing.org
Over the past decade, major discoveries in retrotransposon biology have depicted the
neural genome as a dynamic structure during life. In particular, the retrotransposon LINE-1 …

The role of DNA methylation in the pathophysiology and treatment of bipolar disorder

GR Fries, Q Li, B McAlpin, T Rein, C Walss-Bass… - Neuroscience & …, 2016 - Elsevier
Bipolar disorder (BD) is a multifactorial illness thought to result from an interaction between
genetic susceptibility and environmental stimuli. Epigenetic mechanisms, including DNA …

[图书][B] Biosocial education: The social and biological entanglements of learning

D Youdell, MR Lindley - 2018 - taylorfrancis.com
In this groundbreaking text, Youdell and Lindley bring together cutting-edge research from
the fields of biology and social science to explore the complex interactions between the …