Sequencing-based analyses of microbiomes have traditionally focused on addressing the question of community membership and profiling taxonomic abundance through amplicon …
The human gut microbiome harbors hundreds of bacterial species with diverse biochemical capabilities. Dozens of drugs have been shown to be metabolized by single isolates from …
Antibiotic resistance is a natural feature of diverse microbial ecosystems. Although recent studies of the antibiotic resistome have highlighted barriers to the horizontal transfer of …
Soil plays a crucial role in ecosystem functioning. In the 1990s ecosystem services (ES) research focused on developing the concept and framework and only a few studies linked …
U Markel, KD Essani, V Besirlioglu, J Schiffels… - Chemical Society …, 2020 - pubs.rsc.org
Enzymes are versatile catalysts and their synthetic potential has been recognized for a long time. In order to exploit their full potential, enzymes often need to be re-engineered or …
In soil ecosystems, microorganisms produce diverse secondary metabolites such as antibiotics, antifungals and siderophores that mediate communication, competition and …
The wellbeing of soils is crucial for securing food production worldwide. The soil health (SH) concept has been introduced due to an evolving understanding that soil is not just a growing …
EA Franzosa, T Hsu, A Sirota-Madi… - Nature Reviews …, 2015 - nature.com
High-throughput DNA sequencing has proven invaluable for investigating diverse environmental and host-associated microbial communities. In this Review, we discuss …
GM Cragg, DJ Newman - Biochimica et Biophysica Acta (BBA)-General …, 2013 - Elsevier
BACKGROUND: Nature has been a source of medicinal products for millennia, with many useful drugs developed from plant sources. Following discovery of the penicillins, drug …