N Toda, K Ayajiki, T Okamura - Pharmacology & therapeutics, 2005 - Elsevier
The discovery of nitric oxide (NO) as an intercellular messenger or neurotransmitter opened a new era for identifying the important mechanisms underlying physiological and …
PJ Pagano, JK Clark… - Proceedings of the …, 1997 - National Acad Sciences
Superoxide anion (O2−) plays a key role in the endogenous suppression of endothelium- derived nitric oxide (NO) bioactivity and has been implicated in the development of …
R de la Puerta, MEM Domı́nguez, V Ruı́z-Gutı́errez… - Life Sciences, 2001 - Elsevier
The major phenolics from the polar fraction of virgin olive oil (caffeic acid, oleuropein, tyrosol and hydroxytyrosol) have well-established antioxidant activities but their effects on reactive …
ME Cifuentes, FE Rey, OA Carretero… - American Journal of …, 2000 - journals.physiology.org
Although NAD (P) H oxidase-derived superoxide (O2−) is increased during the development of angiotensin II (ANG II)-dependent hypertension, vascular regulation at the protein level …
N Toda, AG Herman - Pharmacological reviews, 2005 - ASPET
Gastrointestinal (GI) smooth muscle responses to stimulation of the nonadrenergic noncholinergic inhibitory nerves have been suggested to be mediated by polypeptides, ATP …
DW Laight, AV Kaw, MJ Carrier… - British journal of …, 1998 - Wiley Online Library
Nitric oxide (NO)‐mediated, endothelium‐dependent vasodilator function in rat aortic smooth muscle was investigated in an in vitro model of endogenous vascular superoxide …
S Dudgeon, DP Benson, A MacKenzie… - British journal of …, 1998 - ncbi.nlm.nih.gov
Recovery by ascorbate of impaired nitric oxide-dependent relaxation resulting from oxidant stress in rat aorta Page 1 Recovery by ascorbate of impaired nitric oxide-dependent …
A Gibson, E Lilley - General Pharmacology: The Vascular System, 1997 - Elsevier
1. There is now strong evidence that the L-arginine/nitric oxide (NO) pathway generates the transmitter released from certain nonadrenergic, noncholinergic nerves that mediate smooth …
E Lilley, A Gibson - British journal of pharmacology, 1996 - Wiley Online Library
1 The potential protective effect of several antioxidants [Cu/Zn superoxide dismutase (Cu/Zn SOD), ascorbate, reduced glutathione (GSH), and α‐tocopherol (α‐TOC)] on relaxations of …