Current therapeutic approaches and promising perspectives of using bioengineered peptides in fighting chemoresistance in triple-negative breast cancer

M Azari, F Bahreini, VN Uversky, N Rezaei - Biochemical Pharmacology, 2023 - Elsevier
Breast cancer is a collation of malignancies that manifest in the mammary glands at the early
stages. Among breast cancer subtypes, triple-negative breast cancer (TNBC) shows the …

The power of phages: revolutionizing cancer treatment

MS Islam, J Fan, F Pan - Frontiers in Oncology, 2023 - frontiersin.org
Cancer is a devastating disease with a high global mortality rate and is projected to increase
further in the coming years. Current treatment options, such as chemotherapy and radiation …

Albumin nanoparticles surface decorated with a tumor-homing peptide help in selective killing of triple-negative breast cancer cells

S Pal, FP Mohny, SG Choudhury… - … Applied Materials & …, 2023 - ACS Publications
In this article, we describe a method of delivery of doxorubicin using a novel tumor-homing
peptide-based albumin nanoparticle system to triple-negative breast cancer cells (TNBC) …

Codelivery of metformin and methotrexate with optimized chitosan nanoparticles for synergistic triple-negative breast cancer therapy in vivo

A Karimian-Shaddel, H Dadashi, M Mashinchian… - International Journal of …, 2024 - Elsevier
The development of effective therapeutic strategies for triple-negative breast cancer (TNBC),
an aggressive subtype with limited treatment options, remains a critical challenge. This study …

MUC16 promotes triple-negative breast cancer lung metastasis by modulating RNA-binding protein ELAVL1/HUR

S Chaudhary, MI Appadurai, SK Maurya… - Breast Cancer …, 2023 - Springer
Background Triple-negative breast cancer (TNBC) is highly aggressive with an increased
metastatic incidence compared to other breast cancer subtypes. However, due to the …

Tetramodal imaging and synergistic cancer radio-chemotherapy enabled by multiple component-encapsulated zeolitic imidazolate frameworks

Y Kang, X Yu, X Fan, Aodenggerile, S Zhao, C Tu… - ACS …, 2020 - ACS Publications
The abundant species of functional nanomaterials have attracted tremendous interests as
components to construct multifunctional composites for cancer theranostics. However, their …

Anti-triple-negative breast cancer metastasis efficacy and molecular mechanism of the STING agonist for innate immune pathway

X Lu, X Wang, H Cheng, X Wang, C Liu… - Annals of Medicine, 2023 - Taylor & Francis
Background With high recurrence and metastatic rates, triple-negative breast cancer (TNBC)
has few therapy choices. The innate immune stimulator of interferon genes protein (STING) …

Enhanced anti-tumor and anti-metastatic activity of quercetin using pH-sensitive Alginate@ ZIF-8 nanocomposites: in vitro and in vivo study

N Rostamkhani, M Salimi, A Adibifar, Z Karami… - …, 2024 - iopscience.iop.org
Quercetin (Qc) possesses anti-cancer properties, such as cell signaling, growth
suppression, pro-apoptotic, anti-proliferative, and antioxidant effects. In this study, we …

Bioguided fractionation of local plants against matrix metalloproteinase9 and its cytotoxicity against breast cancer cell models: In silico and in vitro study

M Hariono, R Rollando, J Karamoy, P Hariyono… - Molecules, 2020 - mdpi.com
Matrix metalloproteinase9 (MMP9) is known to be highly expressed during metastatic cancer
where most known potential inhibitors failed in the clinical trials. This study aims to select …

[HTML][HTML] Tea tree oil presents in vitro antitumor activity on breast cancer cells without cytotoxic effects on fibroblasts and on peripheral blood mononuclear cells

CE Assmann, FC Cadoná, BSR Bonadiman… - Biomedicine & …, 2018 - Elsevier
The purpose of this study was to investigate some possible mechanisms underlying the in
vitro antitumor activity of tea tree oil (TTO) on human and mouse breast cancer cells (MCF-7 …