The dorsal striatum is a large forebrain region involved in action initiation, timing, control,
learning and memory. Learning and remembering skilled movement sequences requires the …

Adaptation of the nervous system to different chemical and physiologic conditions is
important for the homeostasis of brain processes and for learning and remembering …

BACKGROUND: Previous studies have shown that cerebrospinal fluid (CSF) from
schizophrenic patients contains significantly higher levels of the endogenous cannabinoid …

Anandamide is a lipid mediator that acts as an endogenous ligand of CB1 receptors. These
receptors are also the primary molecular target responsible for the pharmacological effects …

The endogenous cannabinoid system is an important regulatory system involved in
physiological homeostasis. Endocannabinoid signaling is known to modulate neural …

The ability of cannabinoids to modulate both inflammatory and degenerative neuronal
damage prompted investigations on the potential benefits of such compounds in multiple …

Despite extensive research on the trafficking of anandamide (AEA) across cell membranes,
little is known about the membrane transport of other endocannabinoids, such as 2 …

Acute rewarding properties are essential for the establishment of cocaine addiction, and
multiple neurochemical processes participate in this complex behavior. In the present study …

Future therapies for diseases associated with altered dopaminergic signaling, including
Parkinson's disease, schizophrenia and drug addiction or drug dependence may …

The endocannabinoid system plays a regulatory role in a number of physiological processes
and has been found altered in different pathological conditions, including movement …